ChemicalBook > CAS DataBase List > (R)-4-Benzyl-2-oxazolidinone
(R)-4-Benzyl-2-oxazolidinone
(R)-4-Benzyl-2-oxazolidinone
- CAS No.102029-44-7
- Chemical Name:(R)-4-Benzyl-2-oxazolidinone
- CBNumber:CB7852611
- Molecular Formula:C10H11NO2
- Formula Weight:177.2
- MOL File:102029-44-7.mol
(R)-4-Benzyl-2-oxazolidinone Property
- Melting point 88-90 °C
- alpha 62 º (C=1, CHCl3)
- Boiling point 309.12°C (rough estimate)
- Density 1.1607 (rough estimate)
- refractive index 14.5 ° (C=5, MeOH)
- storage temp. Inert atmosphere,Room Temperature
- solubility Chloroform (Slightly)
- form Crystalline Powder
- pka 12.78±0.40(Predicted)
- color White to almost white
- optical activity [α]18/D +64°, c = 1 in chloroform
- Water Solubility Insoluble in water. Soluble in Chloroform.
- Sensitive Hygroscopic
- BRN 4782551
- CAS DataBase Reference 102029-44-7(CAS DataBase Reference)
- UNSPSC Code 12352005
- NACRES NA.22
Safety
- Hazard Codes :Xi
- Risk Statements :36/37/38
- Safety Statements :22-24/25-36-26
- WGK Germany :3
- F :3-10
- HS Code :29349990
-
NFPA 704:
1 2 0
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H320
- Precautionary statements P264-P305+P351+P338+P337+P313
(R)-4-Benzyl-2-oxazolidinone Price
More Price(4)
- Brand: Sigma-Aldrich(India)
- Product number: 300977
- Product name : (R)-4-Benzyl-2-oxazolidinone
- Purity: 99%
- Packaging: 5G
- Price: ₹6018.7
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: 300977
- Product name : (R)-4-Benzyl-2-oxazolidinone
- Purity: 99%
- Packaging: 25G
- Price: ₹31922.93
- Updated: 2022/06/14
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: B1786
- Product name : (R)-4-Benzyl-2-oxazolidinone
- Purity: min. 98.0 %
- Packaging: 5G
- Price: ₹3400
- Updated: 2022/05/26
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: B1786
- Product name : (R)-4-Benzyl-2-oxazolidinone
- Purity: min. 98.0 %
- Packaging: 25G
- Price: ₹14900
- Updated: 2022/05/26
- Buy: Buy
(R)-4-Benzyl-2-oxazolidinone Chemical Properties,Usage,Production
- Description (R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.
- Chemical Properties white to light yellow crystal powde
- Uses (R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.
- Uses intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan
-
References
http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.
(R)-4-Benzyl-2-oxazolidinone Preparation Products And Raw materials
Raw materials
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102029-44-7, (R)-4-Benzyl-2-oxazolidinoneRelated Search:
- (-)-4-Benzyl-2-oxazolidinone,(S)-(-)-4-BENZYL-2-OXAZOLIDINONE,(S)-4-BENZYL-2-OXAZOLIDINONE,4-(S)-Benzyl-2-oxazolidinone,(S)-4-Benzyl-2-oxazolidinone, >99% ee (S)-(+)-4-Phenyl-2-oxazolidinone (N-CHLOROACETYL)-(4S)-BENZYL-2-OXAZOLIDINONE N-PROPIONYL-(4R)-BENZYL-2-OXAZOLIDINONE,N-3-PROPIONYL-(4R)-BENZYL-2-OXAZOLIDINONE (S)-4-(4'-Nitrobenzyl)-1,3-oxazolidine-2-one (R)-(+)-5,5-DIPHENYL-4-BENZYL-2-OXAZOLIDINONE (R)-4-Benzyl-2-oxazolidinone 4-(4-Hydrazinobenzyl)-2-oxazolidinone N-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE,N-3-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE S/R-4-BENZYL-2-OXAZOLIDINONE 2-Oxazolidone (R)-4-(4-AMINOMETHYL-BENZYL)-OXAZOLIDIN-2-ONE (3S,4R)-4-BENZYL-3-(3-METHYLPENTANOYL)-OXAZOLIDIN-2-ONE (N-ACETYL)-(4R)-BENZYL-2-OXAZOLIDINONE Z-D-Phenylalanine N-carboxyanhydride (R)-4-BENZYL-OXAZOLIDINE-2,5-DIONE (R)-4-BENZYL-3-(3-CYCLOPENTYL-PROPIONYL)-OXAZOLIDIN-2-ONE (R)-4-BENZYL-3-(3-CYCLOPROPYL-PROPIONYL)-OXAZOLIDIN-2-ONE
- Oxazolidinone Derivatives
- Oxazolidinone
- Chiral Compounds
- chiral
- Chiral chemicals
- Synthetic Organic Chemistry
- Glycidyl Compounds, etc. (Chiral)
- Chiral Building Blocks
- Asymmetric Synthesis
- Ketone
- Heterocycles
- Chiral Reagents
- Aromatics
- Peptide
- Chiral Auxiliaries
- Asymmetric Synthesis
- 系列2
- 化工原料及中间体
- 产品目录
- 其它原料及中间体
- 高端化学
- 原料药
- 化工原料
- 对照品
- 氨基酸衍生物
- 有机化工原料
- 阿利克仑中间体
- 医药原料
- 化学试剂
- 医用原料
- 氟化物
- 中间体-有机中间体
- 药物杂质及中间体
- 化工中间体
- 有机原料-酮
- 其他化学试剂
- 杂环砌块
- 有机原料
- 中间体
- 农药杀菌剂
- 化肥与农药
- 手性化合物
- 医药中间体
- 噁唑
- 通用试剂
- 恶唑
- Oxazolidinone Derivatives
- Chiral Auxiliaries
- Glycidyl Compounds, etc. (Chiral)
- Asymmetric Synthesis
- Chiral Building Blocks
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