ChemicalBook > CAS DataBase List > Mannose Triflate
Mannose Triflate
Mannose Triflate
- CAS No.92051-23-5
- Chemical Name:Mannose Triflate
- CBNumber:CB7774955
- Molecular Formula:C15H19F3O12S
- Formula Weight:480.36
- MOL File:92051-23-5.mol
Mannose Triflate Property
- Melting point 118-122 °C
- alpha [α]D20 -14~-17゜(c=1,CHCl3)
- Boiling point 481.6±45.0 °C(Predicted)
- Density 1.50±0.1 g/cm3(Predicted)
- refractive index -16 ° (C=1, CHCl3)
- storage temp. -20°C
- solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
- form Solid
- color White to Off-White
- optical activity [α]22/D -16°, c = 1 in chloroform
- BRN 4341413
- InChI InChI=1/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/s3
- InChIKey OIBDVHSTOUGZTJ-UBBZJQTNNA-N
- SMILES [C@H]1(OC(=O)C)[C@H](OC(=O)C)[C@H](O[C@@H](OC(=O)C)[C@H]1OS(=O)(=O)C(F)(F)F)COC(=O)C |&1:0,5,10,12,17,r|
- FDA UNII 0KI8FFQ6TT
- UNSPSC Code 41116107
- NACRES NA.24
Safety
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H335-H315-H319
- Precautionary statements P261-P280-P271
Mannose Triflate Price
More Price(8)
- Brand: Sigma-Aldrich(India)
- Product number: M1568
- Product name : Mannose triflate
- Purity: For PET imaging, ≥98% (TLC)
- Packaging: 20MG
- Price: ₹2359.85
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: M1568
- Product name : Mannose triflate
- Purity: For PET imaging, ≥98% (TLC)
- Packaging: 25MG
- Price: ₹3031
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: M1568
- Product name : Mannose triflate
- Purity: For PET imaging, ≥98% (TLC)
- Packaging: 100MG
- Price: ₹7328.53
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: M1568
- Product name : Mannose triflate
- Purity: For PET imaging, ≥98% (TLC)
- Packaging: 10X25MG
- Price: ₹15219.95
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: 655112
- Product name : β-D-Mannopyranose 1,3,4,6-tetra-O-acetate 2-O-trifluoromethanesulfonate
- Purity: 98%
- Packaging: 100MG
- Price: ₹4340.83
- Updated: 2022/06/14
- Buy: Buy
Mannose Triflate Chemical Properties,Usage,Production
- Description Mannose triflate is a glucose analog. Mannose triflate is a well-known precursor for 18F-FDG synthesis for PET applications. 18F-FDG is an imaging technique for cancer.
- Physical properties White to off-white powder or crystal
- Uses 1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethanesulfonyl-beta-D-mannopyranose is a radiolabelled pharmaceutical preparation for diagnostic aims used in positron emission tomography.
- Preparation The tetraacetyl mannose (1.8 g, 5 mmol) was dissolved in anhydrous CH2Cl2(14 mL) containing dry pyridine (0.9 mL, 11 mmol). This solution was cooled to -15°C, and trifluoromethanesulfonic anhydride (triflic anhydride) (0.9 mL, 5.2 mmol) was added dropwise over 25 min under a nitrogen atmosphere with vigorous stirring. The mixture was then allowed to reach room temperature overnight. The reaction mixture was successively washed with ice-cold saturated aqueous NaHCO3(50 mL) and water (50 mL). The organic layer was dried over anhydrous Na2SO4, filtered, and concentrated on a rotary evaporator.2-Tf-O-AcManwas isolated by column chromatography on silica with hexane :EtOAc=1: 1 as the eluant as white solid Mannose triflate(1.4 g, 56percent).
Mannose Triflate Preparation Products And Raw materials
Raw materials
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- C15H19F3O12S
- 2964-54-4
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- (TATM)甘露糖三氟磺酸酯
- 92051-23-5
- β-<sc>D</sc>-Mannopyranose 1,3,4,6-tetra-<i>O</i>-acetate 2-<i>O</i>-trifluoromethanesulfonate
- Tetra-<i>O</i>-acetyl-mannose triflate
- β-D-Mannopyranose 1,3,4,6-tetra-O-acetate 2-O-trifluoromethanesulfonate ( TATM)