ChemicalBook > CAS DataBase List > N6-(P-AMINOBENZYL)ADENOSINE
N6-(P-AMINOBENZYL)ADENOSINE
N6-(P-AMINOBENZYL)ADENOSINE
- CAS No.95523-13-0
- Chemical Name:N6-(P-AMINOBENZYL)ADENOSINE
- CBNumber:CB7496943
- Molecular Formula:C17H20N6O4
- Formula Weight:372.38
- MOL File:95523-13-0.mol
N6-(P-AMINOBENZYL)ADENOSINE Property
- Boiling point 749.0±70.0 °C(Predicted)
- Density 1.71±0.1 g/cm3(Predicted)
- storage temp. 2-8°C
- solubility Soluble in DMSO
- pka 13.12±0.70(Predicted)
- form Solid
- color Off-white to light yellow
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
N6-(P-AMINOBENZYL)ADENOSINE Chemical Properties,Usage,Production
- Uses N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5′-Nucleotidase. IC50 value: 29.0 ± 1.7 nM (Ki) Target: Adenosine Receptor
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References
[1] Bhattarai S, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63. DOI:10.1021/acs.jmedchem.5b00802
[2] Chen JB, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6(8):1390-400. DOI:10.1002/cmdc.201100126
[3] Zhu Z, et al. Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorg Med Chem. 2008 Apr 1;16(7):3848-65. DOI:10.1016/j.bmc.2008.01.044
N6-(P-AMINOBENZYL)ADENOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
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