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4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one

4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Structure
4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
  • CAS No.1445994-28-4
  • Chemical Name:4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
  • CBNumber:CB73684101
  • Molecular Formula:C20H15F2N3O2
  • Formula Weight:367.35
  • MOL File:1445994-28-4.mol
4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Property
  • Boiling point 553.7±50.0 °C(Predicted)
  • Density 1.418±0.06 g/cm3(Predicted)
  • pka 14.88±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Chemical Properties,Usage,Production

  • Uses PROTAC BRD4 ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). PROTAC BRD4 ligand-3 can be used for synthesis PROTAC BRD4 Degrader-27 (HY-162875)[1].
  • References [1] Kong Y, et al. BRD4-specific PROTAC inhibits basal-like breast cancer partially through downregulating KLF5 expression. Oncogene. 2024 Sep;43(39):2914-2926. DOI:10.1038/s41388-024-03121-1
4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Suppliers
Global(1)Suppliers
  • Supplier： Wuxi AppTec
  • Tel：022-59987777 <br/>13552403979
  • Email：jia_guoqiang@wuxiapptec.com
  • Country：China
  • ProdList：22345
  • Advantage：58
4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one Spectrum
  • 4-(5-氨基-2-(2,4-二氟苯氧基)苯基)-6-甲基-1H-吡咯并[2,3-C]吡啶-7(6H)-酮
  • 1445994-28-4
  • 7H-Pyrrolo[2,3-c]pyridin-7-one, 4-[5-amino-2-(2,4-difluorophenoxy)phenyl]-1,6-dihydro-6-methyl-
  • 4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one

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