ChemicalBook > CAS DataBase List > 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Structure
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
  • CAS No.1479-24-9
  • Chemical Name:3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
  • CBNumber:CB7331507
  • Molecular Formula:C11H11FO3
  • Formula Weight:210.2
  • MOL File:1479-24-9.mol
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Property
  • Boiling point 124-125℃ (1.5 Torr)
  • Density 1.164 g/mL at 25 °C(lit.)
  • refractive index n20/D 1.516(lit.)
  • Flash point >230 °F
  • storage temp. Keep in dark place,Inert atmosphere,Room temperature
  • form Liquid
  • pka 10.03±0.46(Predicted)
  • color Colorless to Light orange to Yellow
  • UNSPSC Code 12352100
  • NACRES NA.22
Safety
  • WGK Germany  :3
  • HS Code  :2918.30.9000
  • NFPA 704:
    1
    0 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: 225134
  • Product name : Ethyl (2-fluorobenzoyl)acetate
  • Purity: technical grade
  • Packaging: 1G
  • Price: ₹3247.5
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 225134
  • Product name : Ethyl (2-fluorobenzoyl)acetate
  • Purity: technical grade
  • Packaging: 10G
  • Price: ₹18077.75
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: E1097
  • Product name : Ethyl (2-Fluorobenzoyl)acetate
  • Purity: min. 98.0 %
  • Packaging: 5G
  • Price: ₹5000
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: E1097
  • Product name : Ethyl (2-Fluorobenzoyl)acetate
  • Purity: min. 98.0 %
  • Packaging: 25G
  • Price: ₹16800
  • Updated: 2022/05/26
  • Buy: Buy

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Chemical Properties,Usage,Production

  • Uses Ethyl (2-fluorobenzoyl)acetate may be used in chemical synthesis.
  • Synthesis
    Ethanol

    64-17-5

    1,3-Dioxane-4,6-dione, 5-(2-fluorobenzoyl)-2,2-dimethyl-

    223679-79-6

    3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

    1479-24-9

    GENERAL METHOD: An appropriate amount of diketone (9a or 9b) (0.3 mol) was mixed with ethanol (500 mL), heated to 80 °C and refluxed for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure to give the target product ester (10a or 10b) in the form of a red oil. 7.10.1 Preparation of ethyl 3-(2-fluorophenyl)-3-oxopropanoate (10a): the product obtained was a red oily material in 85% yield; mass spectrum (ESI) m/z: 233.1 [M + Na]? , 443.1 [2M + Na]?

  • References [1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 11, p. 2843 - 2855
    [2] Archiv der Pharmazie, 2013, vol. 346, # 7, p. 521 - 533
    [3] Patent: EP2799437, 2014, A1. Location in patent: Paragraph 0057
    [4] Patent: US2014/364431, 2014, A1. Location in patent: Paragraph 0188
    [5] Patent: WO2017/37672, 2017, A1. Location in patent: Page/Page column 48
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Suppliers
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3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Spectrum
1479-24-9, 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTERRelated Search:
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  • 高端化学
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  • 通用试剂
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  • (2-氟苯甲酰)乙酸乙酯Ethyl (2-fluorobenzoyl)acetate
  • (2-氟苯甲酰)乙酸乙酯Ethyl (2-fluorobenzoyl)acetate
  • (2-氟苯甲酰)乙酸乙酯,试剂级
  • (2-氟苯甲酰基)乙酸乙酯
  • (2-氟苯甲酰)乙酸乙酯
  • 3-(2-氟苯基)-3-氧代-丙酸乙酯
  • 邻氟苯甲酰乙酸乙酯
  • 乙基 (2-氟苯甲酰基)乙酸酯
  • 1479-24-9
  • Benzenepropanoic acid, 2-fluoro-β-oxo-, ethyl ester
  • RMA-126
  • Benzenepropanoic acid, 2-fluoro-β-oxo-, ethyl ester
  • Ethyl(2-Fluorobenzoyl)acetate&gt
  • 2-[(2-fluorophenyl)-oxomethyl]butanoate
  • 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
  • ETHYL 3-(2-FLUOROPHENYL)-3-OXOPROPANOATE
  • ETHYL 2-FLUOROBENZOYLACETATE
  • Benzenepropanoic acid, 2-fluoro-b-oxo-, ethyl ester
  • β-Oxo-2-fluorobenzenepropanoic acid ethyl ester
  • 3-Oxo-3-(2-fluorophenyl)propionic acid ethyl ester
  • 2-Fluorobenzoylacetic acid ethyl ester
  • Ethyl 3-(2-fluorophenyl)-3-oxo-propionate
  • Ethyl (2-fluorobenzoyl)acetate technical grade
  • NSC 166423
  • Ethyl 3-oxo-3-(2-fluorophenyl)propionate

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