ChemicalBook > CAS DataBase List > Fluorescein-PEG2-Azide
Fluorescein-PEG2-Azide
- CAS No.1146195-72-3
- Chemical Name:Fluorescein-PEG2-Azide
- CBNumber:CB73062495
- Molecular Formula:C27H25N5O7S
- Formula Weight:563.59
- MOL File:1146195-72-3.mol
Fluorescein-PEG2-Azide Property
- solubility Soluble in DMSO, DMF, DCM
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Fluorescein-PEG2-Azide Chemical Properties,Usage,Production
- Description Fluorescein-PEG2-azide is a green emitting fluorescent dye derivitative with excitation/emmission maximum 494/517 nm containing an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding.
- Uses Fluorescein-thiourea-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fluorescein-thiourea-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- IC 50 PEGs
- References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fluorescein-PEG2-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
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1146195-72-3, Fluorescein-PEG2-AzideRelated Search:
- CI 45350 FLUORESCEIN MALEIMIDE 5(6)-(BIOTINAMIDOCAPROYLAMIDO) PENTYLTHI Flurescein-NHS ester Fluorescein-PEG3-(N-Boc)-Amine 3H-IndoliuM, 2-[5-[1-[6-[(3-azidopropyl)aMino]-6-oxohexyl]-1,3-dihydro-3,3-diMethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-triMethyl-5-sulfo-, inner salt Pyrene -PEG3-azide DNP-PEG3-azide Azidoacetic acid NHS ester Methylamino-PEG3-azide BDP FL azide diSulfo-Cy5 azide Fluorescein-PEG4-azide Lipoamido-PEG3-Azide FAM azide, 6-isomer Fluorescein-PEG6-NHS ester Fluorescein-PEG3-N3
- 抑制剂
- 高端化学
- 化合物 FLUORESCEIN-THIOUREA-PEG2-AZIDE
- 荧光素-PEG2-叠氮化物
- 5-异硫氰酸荧光素-二聚乙二醇-叠氮
- 5-FITC-二聚乙二醇-叠氮
- 荧光素-硫脲基-PEG2-叠氮化物
- 荧光素-二聚乙二醇-叠氮
- 1146195-72-3
- FITC-PEG2-N3
- 5-FITC-PEG2-azide
- Fluorescein-thiourea-PEG2-azide
- Fluorescein-PEG2-N3
- Fluorescein-PEG8-Azide
- Fluorescein-PEG2-Azide
