Synthesis
ChemicalBook > CAS DataBase List > 2,4-DIFLUOROPYRIMIDINE

2,4-DIFLUOROPYRIMIDINE

Synthesis
2,4-DIFLUOROPYRIMIDINE Structure
2,4-DIFLUOROPYRIMIDINE
  • CAS No.2802-61-1
  • Chemical Name:2,4-DIFLUOROPYRIMIDINE
  • CBNumber:CB7263268
  • Molecular Formula:C4H2F2N2
  • Formula Weight:116.07
  • MOL File:2802-61-1.mol
2,4-DIFLUOROPYRIMIDINE Property
  • Boiling point 118-120 °C
  • Density 1.359 g/mL at 25 °C
  • refractive index n20/D 1.432
  • Flash point 106 °F
  • pka -2.52±0.20(Predicted)
  • form liquid
  • color Clear, colourless
  • CAS DataBase Reference 2802-61-1(CAS DataBase Reference)
  • UNSPSC Code 12352100
  • NACRES NA.22
Safety
  • Hazard Codes  :Xn,Xi
  • Risk Statements  :10-22-37/38-41
  • Safety Statements  :26-39
  • RIDADR  :UN 1993 3/PG 3
  • WGK Germany  :3
  • Hazard Note  :Irritant
  • HazardClass  :3
  • PackingGroup  :III
  • HS Code  :29335990
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H226-H302-H315-H318-H335
  • Precautionary statements P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
2,4-DIFLUOROPYRIMIDINE Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: 661082
  • Product name : 2,4-Difluoropyrimidine
  • Purity: 97%
  • Packaging: 100MG
  • Price: ₹4070.2
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 661082
  • Product name : 2,4-Difluoropyrimidine
  • Purity: 97%
  • Packaging: 500MG
  • Price: ₹14126.63
  • Updated: 2022/06/14
  • Buy: Buy

2,4-DIFLUOROPYRIMIDINE Chemical Properties,Usage,Production

  • Synthesis Crown ethers are able to enhance the performance of KF in two ways. Firstly, they complex the potassium cation making a better fluoride source and secondly they increase the solubility of KF in the solvent. KF with a catalytic amount of dicyclohexano-18-crown-6 in tetraglyme converted 2,4-dichloropyrimidine into 2,4-difluoropyrimidine.
  • Uses 2,4-Difluoropyrimidine can be used as a starting material to synthesize:
    • 3-Pyrimidin-4-yl-oxazolidin-2-one derivatives as mutant isocitrate dehydrogenase (IDH1) inhibitors.
    • N,N′-(1,4-phenylenebis(methylene))bis(2-fluoropyrimidin-4-amine) as chemokine receptor type 4 antagonists.

  • Synthesis Reference(s) Journal of Heterocyclic Chemistry, 22, p. 149, 1985 DOI: 10.1002/jhet.5570220137
2,4-DIFLUOROPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-DIFLUOROPYRIMIDINE Suppliers
Global(85)Suppliers
  • Supplier：
    Alchem Pharmtech,Inc.
  • Tel：8485655694
  • Email：sales@alchempharmtech.com
  • Country：United States
  • ProdList：63687
  • Advantage：58
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
  • Supplier：
    Coresyn Pharmatech Co., Ltd.
  • Tel：+86-571-86626709<br/>+86-18157142896
  • Email：cbc@coresyn.com
  • Country：China
  • ProdList：9984
  • Advantage：58
2,4-DIFLUOROPYRIMIDINE Spectrum
2802-61-1, 2,4-DIFLUOROPYRIMIDINERelated Search:
  • Pyrimidines
  • Heterocyclic Building Blocks
  • Building Blocks
  • Pyrazines, Pyrimidines & Pyridazines
  • Heterocyclic Compounds
  • Pyrazines, Pyrimidines & Pyridazines
  • Halides
  • PYRIMIDINE
  • 化工中间体
  • 中间体化合物
  • 高端化学
  • 氮杂环
  • 芳香氟化物
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrimidines
  • 2,4-二氟嘧啶,98%
  • 2,4-二氟嘧啶
  • 2802-61-1
  • 2,4-<WBR>Difluoropyrimidine
  • 2,4-DIFLUOROPYRIMMIDINE
  • 2,4-DIFLUOROPYRIMIDINE ISO 9001：2015 REACH
  • Pyrimidine, 2,4-difluoro-
  • EOS-61621
  • 2,4-Difluoropyrimidine98%
  • 2,4-Difluoropyrimidine 98%
  • Pyrimidine, 2,4-difluoro- (6CI,8CI,9CI)
  • NSC 331813
  • 2,4-DIFLUOROPYRIMIDINE

Home

My