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ALPHA-ENDORPHIN

ALPHA-ENDORPHIN Structure
ALPHA-ENDORPHIN
  • CAS No.59004-96-5
  • Chemical Name:ALPHA-ENDORPHIN
  • CBNumber:CB7261017
  • Molecular Formula:C77H120N18O26S
  • Formula Weight:1745.95
  • MOL File:59004-96-5.mol
ALPHA-ENDORPHIN Property
  • RTECS JZ2270000
  • storage temp. −20°C
  • solubility ≥174.5 mg/mL in DMSO; insoluble in EtOH; ≥52.7 mg/mL in H2O
  • form White powder
  • Stability Hygroscopic
Safety
  • Safety Statements  :22-24/25
  • WGK Germany  :3
  • F  :10
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

ALPHA-ENDORPHIN Chemical Properties,Usage,Production

  • Uses An opioid peptide and substrate for transglutaminase
  • Biological Activity endorphins are endogenous opioid peptides that function as neurotransmitters(1). they are produced by the pituitary gland and the hypothalamus in vertebrates during exercise, excitement, pain, consumption of spicy food, love and orgasm, and they resemble the opiates in their abilities to produce analgesia and a feeling of well-being.the term implies a pharmacological activity (analogous to the activity of the corticosteroid category of biochemicals) as opposed to a specific chemical formulation. it consists of two parts: endo- and -orphin; these are short forms of the words endogenous and morphine(2), beta-endorphin (β-endorphin) is released into blood from the pituitary gland and into the spinal cord and brain from hypothalamic neurons. the β-endorphin that is released into the blood cannot enter the brain in large quantities because of the blood–brain barrier, so the physiological importance of the β-endorphin that can be measured in the blood is far from clear. β-endorphin is a cleavage product of pro-opiomelanocortin (pomc), which is also the precursor hormone for adrenocorticotrophic hormone (acth). the behavioural effects of β-endorphin are exerted by its actions in the brain and spinal cord, and it is presumed that the hypothalamic neurons are the major source of β-endorphin at these sites. in situations where the level of acth is increased (e.g., cushing’s syndrome), the level of endorphins also increases slightly(3).figure1 formula of a-endorphinfigure 2 mechanism of endorphin to inhibit lhrh release
  • IC 50 μ Opioid Receptor/MOR
  • References 1. Oswald Steward: Functional neuroscience (2000), page 116.2. Goldstein A, Lowery PJ (September 1975). "Effect of the opiate antagonist naloxone on body temperature in rats". Life Sciences 17 (6): 927–31.3. Simantov R, Snyder S (1976). "Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor". Proc Natl Acad Sci USA 73 (7): 2515–9.
ALPHA-ENDORPHIN Preparation Products And Raw materials
Raw materials
Preparation Products
ALPHA-ENDORPHIN Suppliers
Global(130)Suppliers
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    BOC Sciences
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    career henan chemical co
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    TargetMol Chemicals Inc.
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  • Email：marketing@targetmol.com
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ALPHA-ENDORPHIN Spectrum
59004-96-5, ALPHA-ENDORPHINRelated Search:
  • Peptide
  • Neuroscience
  • 目录多肽
  • 抑制剂
  • 蛋白质电泳和蛋白质印迹
  • 目录肽
  • 细胞生物学
  • 细胞信号和神经生物学
  • 多肽
  • BioChemical
  • Protein Analysis
  • Proteomics and Protein Expression
  • Peptide and protein standards for mass spectrometry analysis
  • Mass Spectrometry
  • C77H120N18O26S
  • C158H251N39O46S1
  • Α-ENDORPHIN(HUMAN) 人Α-内啡肽|CAS 59004-96-5
  • 伪-ENDORPHIN HUMAN
  • SH-寡肽-6
  • 内啡肽A-ENDORPHIN
  • Α-内啡肽
  • Α-内啡肽, ≥97% (HPLC)
  • ALPHA-内啡肽
  • Α-内啡肽
  • 59004-96-5
  • α-Endorphin (human, mouse, rat, porcine, bovine, ovine)
  • 59004-96-5/61214-51-5
  • alpha Endorphin acetate,alphaEndorphin acetate
  • alpha-Endorphin acetate (59004-96-5 Free base)
  • alpha-Endorphin acetate
  • ALPHA-ENDORPHIN USP/EP/BP
  • α-Endorphin
  • -Endorphin (human, mouse, rat, porcine, bovine, ovine)
  • α-Endorphin human, ≥97% (HPLC)
  • β-Lipotropin (61-76), human, synthetic, β-Lipotropin 61-76, LPH (61-76), Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr
  • TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR: YGGFMTSEKSQTPLVT
  • a-Endorphin
  • β-lipotropin (61-76), human, synthetic
  • α-endorphin human
  • A-ENDORPHIN HUMAN
  • ALPHA-ENDORPHIN HUMAN SYNTHETIC
  • TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-TYR
  • TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR
  • YGGFMTSEKSQTPLVT
  • ALPHA-ENDORPHIN HUMAN
  • ALPHA-ENDORPHIN
  • H-TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-OH
  • ENDORPHIN, ALPHA-
  • BETA-LIPOTROPIN (61-76)
  • BETA-LIPOTROPIN (59-74) (HUMAN)
  • BETA-ENDORPHIN (1-16)
  • β-Endorphin (1-16)
  • β-Lipotropin 61-76
  • Porcine alpha-endorphin
  • alpha-Endorphin (sheep)
  • alpha-Endorphin (porcine)
  • alpha-Endorphin (pig)
  • b-Endorphin (1-16), b-Lipotropin (59-74) (huMan)

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