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Artemifone

Artemifone Structure
Artemifone
  • CAS No.255730-18-8
  • Chemical Name:Artemifone
  • CBNumber:CB71856023
  • Molecular Formula:C19H31NO6S
  • Formula Weight:401.52
  • MOL File:255730-18-8.mol
Artemifone Property
  • Boiling point 536.5±50.0 °C(Predicted)
  • Density 1.33±0.1 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility DMSO : 130 mg/mL (323.77 mM)
  • form Solid
  • pka 2.99±0.20(Predicted)
  • color White to off-white
  • FDA UNII 796LMW5BUZ
Safety
  • HS Code  :9999999999
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Artemifone Chemical Properties,Usage,Production

  • Uses Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM[1]. Artemisone is also a potent inhibitor of human CMV[2].
  • in vivo

    Artemisone is effectve at inhibiting the parasitaemia in the P. berghei NY susceptible strain, with an ED50 of 9.62 mg/kg via subcutaneous route and 11.67 mg/kg via oral administration[1].
    Artemisone (3, 1, 0.3 and 0.1 mg/kg, s.c.) in combination with ohter antimalarials has enhanced effect against the chloroquine-resistant line P. yoelii NS[1]

  • IC 50 Plasmodium
  • References [1] Vivas L, et al. Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. J Antimicrob Chemother. 2007 Apr;59(4):658-65. DOI:10.1093/jac/dkl563
    [2] Ruiyuan Cao, et al. Anti-SARS-CoV-2 Potential of Artemisinins In Vitro. ACS Infect. Dis. 2020 Jul.
Artemifone Preparation Products And Raw materials
Raw materials
Preparation Products
Artemifone Suppliers
Global(31)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
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    InvivoChem
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  • Email：sales@invivochem.cn
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  • Supplier：
    TargetMol Chemicals Inc.
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  • Email：support@targetmol.com
  • Country：United States
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  • Supplier：
    Aladdin Scientific
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  • Supplier： BOC Sciences
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Artemifone Spectrum
255730-18-8, ArtemifoneRelated Search:
  • 抑制剂
  • C19H31NO6S
  • 青蒿酮,10 MM DMSO 溶液
  • 青蒿酮-[13C4]/精确称量
  • 13C4]-青蒿素
  • 青蒿酮
  • 255730-18-8
  • Artemisone, 10 mM in DMSO
  • 4-((3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)thiomorpholine 1,1-dioxide
  • (5aS,6R,8aR,12S)-3,6-dimethyloctahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,10-dione
  • Cytomegalovirus,Inhibitor,Parasite,CMV,inhibit,Artemisone
  • Thiomorpholine, 4-[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]-, 1,1-dioxide
  • 4-[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]thiomorpholine 1,1-dioxide
  • YHVQDGXHTCSGBJ-AKSSTEKGSA-N
  • BAY 44-9585
  • Artemisone
  • 10alpha-[4'-(S,S-Dioxothiomorpholin-1'-yl)]-10-deoxodihydroartemisinin
  • Artemifone

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