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(+)-Ledene

(+)-Ledene Structure
(+)-Ledene
  • CAS No.21747-46-6
  • Chemical Name:(+)-Ledene
  • CBNumber:CB7153554
  • Molecular Formula:C15H24
  • Formula Weight:204.35
  • MOL File:21747-46-6.mol
(+)-Ledene Property
  • Melting point 269°C
  • Boiling point 268-270 °C (lit.)
  • Density 0.927 g/mL at 20 °C (lit.)
  • refractive index n20/D 1.504
  • storage temp. Refrigerator
  • solubility Chloroform (Sparingly), Ethanol (Slightly)
  • form Oil
  • color Colourless
  • optical activity [α]20/D +68±2°, c = 10% in ethanol
  • BRN 2554786
  • LogP 6.447 (est)
  • FDA UNII 236ZZ41F70
  • UNSPSC Code 12352002
  • NACRES NA.22
Safety
  • Safety Statements  :23-24/25
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
(+)-Ledene Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: 61770
  • Product name : (+)-Ledene
  • Purity: ≥95.0% (sum of enantiomers, GC)
  • Packaging: 250MG
  • Price: ₹11847.08
  • Updated: 2022/06/14
  • Buy: Buy

(+)-Ledene Chemical Properties,Usage,Production

  • Description (+)-Ledene, also called leden or viridiflorene, is an organic compound that belongs to the group of 5, 10-cycloaromadendrane sesquiterpenoids. These compounds are derived from the aromadendrane skeleton through a cyclization reaction between carbon atoms 5 and 10. (+)-Ledene is mainly found in saliva and is considered to have low solubility in water and a relatively neutral nature. In cellular environments, (+)-ledene is predominantly present in the cell membrane (predicted based on logP) and cytoplasm.
  • Uses (+)-Ledene is an essential oil that is synthesized by viridiflorene synthase. It has been studied as an antioxidant, antimicrobial, antibiofilm and to treat various cancers.
  • Definition ChEBI: Viridiflorene is a carbotricyclic sesquiterpene obtained from several natural sources, including Australian Tea Tree oil (Melaleuca alternifolia.) It is a sesquiterpene and a carbotricyclic compound.
  • General Description (+)-Ledene is a naturally occurring sesquiterpene that can be prepared from (+)-aromadendrene via isomerization.
  • References [1] DUC N. TRAN   Prof.??Dr. N C. Biomimetic Synthesis of (+)-Ledene, (+)-Viridiflorol, (?)-Palustrol, (+)-Spathulenol, and Psiguadial A, C, and D via the Platform Terpene (+)-Bicyclogermacrene[J]. Chemistry - A European Journal, 2014. DOI:10.1002/chem.201403082.
    [2] S. L. GWALTNEY   K. J S  S T Sakata. Bridged to Fused Ring Interchange. Methodology for the Construction of Fused Cycloheptanes and Cyclooctanes. Total Syntheses of Ledol, Ledene, and Compressanolide[J]. The Journal of Organic Chemistry, 1996. DOI:10.1021/jo961005a.
(+)-Ledene Preparation Products And Raw materials
Raw materials
Preparation Products
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(+)-Ledene Spectrum
21747-46-6, (+)-LedeneRelated Search:
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  • 抑制剂
  • 高端化学
  • 标准品
  • 植物提取物
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Complex Molecules
  • 愈创奥杂质4
  • 化合物 T25652
  • (1S,2R,4R,11R)-3,3,7,11-四甲基三环[6.3.0.02.4]十一碳-7-烯
  • (+)-喇叭烯
  • 21747-46-6
  • Guaiazulene Impurity 4
  • (+)-Ledene
  • 95.0% (sum of enantiomers, GC)
  • 1H-Cycloprop[e]azulene, 1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-, (1aR,7R,7aS,7bR)-
  • (1aS,7S,7aS,7bS)-1,1,4,7-tetramethyl-1a,2,3,5,6,7,7a,7b-octahydrocyclopropa[e]azulene
  • Varidiflorene
  • 1H-Cycloprop[e]azulene, 1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-, [1aR-(1aalpha,7alpha,7abeta,7balpha)]-
  • 1,1,4,7-Tetramethyl-1a,2,3,5,6,7,7a,7b-octahydro-1H-cyclopropa[e]azulene
  • LEDENE, (+)-(RG)
  • Einecs 244-565-3
  • (1Ar-(1aalpha,7alpha,7abeta,7balpha))-1A,2,3,5,6,7,7A,7B-octahydro-1,1,4,7-tetramethyl-1H-cycloprop(E)azulene
  • (1aR)-1aβ,2,3,5,6,7,7aα,7bβ-Octahydro-1,1,4,7β-tetramethyl-1H-cyclopropa[e]azulene
  • (1aR)-1a,2,3,5,6,7,7aα,7bβ-Octahydro-1,1,4,7β-tetramethyl-1H-cycloprop[e]azulene
  • (+)-LEDENE 95+% MIXTURE OF ISOMERS
  • (1S,2R,3R,11R)-3,3,7,11-TETRAMETHYL-TRICYCLO[6.3.0.0(2.4)]UNDEC-7-ENE
  • [1aR-(1aalpha,7alpha,7abeta,7balpha)]-1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulene
  • (+)-Ledene >=95.0% (sum of enantiomers, GC)
  • Viridflorene