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1,4-Cyclohexanedione

CAS No.637-88-7
Chemical Name:1,4-Cyclohexanedione
CBNumber:CB7138205
Molecular Formula:C6H8O2
Formula Weight:112.13
MOL File:637-88-7.mol

1,4-Cyclohexanedione Property

Melting point 77-78.5 °C (lit.)
Boiling point 112 °C (19.5026 mmHg)
Density 1.0861
refractive index 1.4570 (estimate)
Flash point 132 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol and ethanol.
form Crystalline Powder or Flakes
color Light yellow to yellow or beige
BRN 774152
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
LogP -0.910 (est)
CAS DataBase Reference 637-88-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII BJS27Z99AM
NIST Chemistry Reference 1,4-Cyclohexanedione(637-88-7)
EPA Substance Registry System 1,4-Cyclohexanedione (637-88-7)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :Xi
Safety Statements :22-24/25
WGK Germany :3
F :8
Hazard Note :Irritant
TSCA :Yes
HS Code :29142900

NFPA 704:

	1
1		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P305+P351+P338

1,4-Cyclohexanedione Price More Price(9)

Brand: Sigma-Aldrich(India)
Product number: 125423
Product name : 1,4-Cyclohexanedione
Purity: 98%
Packaging: 10G
Price: ₹2089.23
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 125423
Product name : 1,4-Cyclohexanedione
Purity: 98%
Packaging: 50G
Price: ₹4763
Updated: 2022/06/14
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Brand: ALFA India
Product number: ALF-A11100-36
Product name : 1,4-Cyclohexanedione, 98%
Purity:
Packaging: 500g
Price: ₹19922
Updated: 2022/05/26
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Brand: TCI Chemicals (India)
Product number: C0730
Product name : 1,4-Cyclohexanedione
Purity: min. 98.0 %
Packaging: 25G
Price: ₹3800
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: C0730
Product name : 1,4-Cyclohexanedione
Purity: min. 98.0 %
Packaging: 500G
Price: ₹26200
Updated: 2022/05/26
Buy: Buy

1,4-Cyclohexanedione Chemical Properties,Usage,Production

Chemical Properties tan or yellow crystalline powder
Uses 1,4-Cyclohexanedione is used in the preparation of 1,4 benzoquinone and bromoorganics. It is also used to study the influence of visible light on the bromate-1,4-cyclohexanedione-ferroin oscillating reaction. It plays a vital role in pharmaceuticals, plant growth regulator and as a conducting material.
Definition ChEBI: 1,4-Cyclohexanedione is a cyclohexanedione with oxo substituents at positions 1 and 4.
Preparation Synthesis of 1,4-cyclohexanedione: put diethyl succinylsuccinate into a flask, add a mixture of concentrated sulfuric acid, water and ethanol, reflux in oil solution for 5 days, cool, and neutralize to pH with ammonia water = 8; then extract 4 times with chloroform, and recover the chloroform to obtain the crude product; then the crude product is subjected to vacuum distillation, and the distillate is poured into cold petroleum ether, filtered, and air-dried to obtain 1,4-cyclohexanedi Ketone Products.
Synthesis Reference(s) Synthesis, p. 165, 1981 DOI: 10.1055/s-1981-29377
General Description 1,4-Cyclohexanedione(CHD) undergoes uncatalyzed oscillatory reactions during oxidation by acidic bromate in nitric acid and sulphuric acid solution. It reacts with acidic bromate to form 1,4-dihydroxybenzene which on further oxidation and bromination yields 1,4-benzoquinone and bromoorganics.
Pharmacology The cyclohexanedione (CHD) herbicides inhibit fatty acid synthesis in plants by interfering with the activity of the enzyme Acetyl-Coenzyme A Carboxylase (ACCase). ACCase-inhibiting herbicides provide excellent control of grass weeds in dicotyledonous and some grass crops. A less-sensitive ACCase mediates the intrinsic resistance of dicotyledonous plants to the AOPP and CHD herbicides (34,35). Although grasses are target species of this group of herbicides, not all are equally affected, and sensitivity differences can occur between varieties or even within a genus.