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o-methylisourea

o-methylisourea Structure
o-methylisourea
  • CAS No.2440-60-0
  • Chemical Name:o-methylisourea
  • CBNumber:CB71013558
  • Molecular Formula:C2H6N2O
  • Formula Weight:74.08
  • MOL File:2440-60-0.mol
o-methylisourea Property
  • Melting point 44-45 °C
  • Boiling point 66.9±23.0 °C(Predicted)
  • Density 1.17±0.1 g/cm3(Predicted)
  • solubility free base readily sol most organic solvents. Salts sol water, methanol, ethanol.
  • pka pK1:9.72(＋1) (25°C)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

o-methylisourea Chemical Properties,Usage,Production

  • Uses O-methylisourea can be used in the synthesis of heterocyclic compounds; it is a guanylation reagent and a selective alkylating agent.
  • Application Methyl Carbamimidate is preparation of Ph (3-methoxy-1,2,4-thiadiazol-5-yl)carbamate from O-methylisourea hydrochloride.
  • Preparation O-methylisourea hydrochloride is prepared in 69-80% yield by adding 1.15 equiv  HCl(g) with ice cooling to cyanamide dissolved in excess anhydrous methanol. The free base is obtained  from the salt using powdered KOH in a water-ether mixture or with sodium methoxide in methanol. The  monoacetate salt can be prepared from the free base with 1 equiv of HOAc. Drying: vacuum desiccator  over P2O5.
  • storage Salts are hygroscopic and should be stored in a desiccator even for  brief periods. Heating O-methylisourea to decomposition can liberate toxic fumes of NOx. Use in a fume  hood.
o-methylisourea Preparation Products And Raw materials
Raw materials
Preparation Products
o-methylisourea Suppliers
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o-methylisourea Spectrum
2440-60-0, o-methylisoureaRelated Search:
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  • 2440-60-0
  • o-methylisourea (abbreviate OMIU)
  • Methyl carbamimidate
  • Fluorouracil Impurity 16
  • Carbamimidic acid,methyl ester (9CI)
  • Methoxyformamidine
  • Carbamimidic acid methyl ester
  • ORTHO-METHYLISOUREA
  • o-methylisourea
  • o-Methylisouronium
  • 5329-33-9 (Hydrochloride)
  • 52328-05-9 (Sulfate[2:1])
  • 29427-58-5 (Monosulfate)
  • 24285-39-0 (Sulfate)

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