Description
A group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-
like appearance of two “wing-
like” furan or dihydrofuran rings fused on the opposite sides of the central benzene ring, have been identified with allegedly potent hallucinogenic effects. 2C-
B-
FLY is the dihydrodifuran analog of the Schedule I hallucinogen 4-
bromo-
2,5-
dimethoxyphenethylamine (2C-
B). It is expected to show similar activity to 2C-
B, which acts as a partial agonist at the 5-
HT
2A serotonin receptor and demonstrates high binding affinity for the 5-
HT
2B and 5-
HT
2C serotonin receptors. This product is intended for forensic and research purposes.
Uses
A metabolite of Bromo Dragonfly (B684210).
References
[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] SIMONA PICHINI . Liquid chromatography–atmospheric pressure ionization electrospray mass spectrometry determination of “hallucinogenic designer drugs” in urine of consumers[J]. Journal of pharmaceutical and biomedical analysis, 2008, 47 2: Pages 335-342. DOI:
10.1016/j.jpba.2007.12.039[3] AARON P. MONTE. Dihydrobenzofuran Analogues of Hallucinogens. 3. 1 Models of 4-Substituted (2,5-Dimethoxyphenyl)alkylamine Derivatives with Rigidified Methoxy Groups 2[J]. Journal of Medicinal Chemistry, 1996, 39 15: 2953-2961. DOI:
10.1021/jm960199j[4] JAMES J. CHAMBERS. Enantiospecific Synthesis and Pharmacological Evaluation of a Series of Super-Potent, Conformationally Restricted 5-HT2A/2C Receptor Agonists[J]. Journal of Medicinal Chemistry, 2001, 44 6: 1003-1010. DOI:
10.1021/jm000491y
