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bialamicol
bialamicol
- CAS No.493-75-4
- Chemical Name:bialamicol
- CBNumber:CB6875338
- Molecular Formula:C28H40N2O2
- Formula Weight:436.63
- MOL File:493-75-4.mol
bialamicol Property
- Boiling point 506.6±45.0 °C(Predicted)
- Density 1.040±0.06 g/cm3(Predicted)
- pka 9.67±0.50(Predicted)
- FDA UNII TA5NM093QJ
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
bialamicol Chemical Properties,Usage,Production
- Originator Camoform HCl,Parke Davis,US,1956
- Uses Anti-amebic.
- Definition ChEBI: Bialamicol is a member of hydroxybiphenyls.
- Manufacturing Process Paraformaldehyde (7.59) (0.25mol) and 18.3 g (0.25 mol) of diethylamine are mixed in 25 cc of alcohol and warmed until a clear solution is obtained. The solution is cooled and mixed with 26.6 g (0.10 mol) of 3,3'-diallyl-4,4'- biphenol in 25 cc of alcohol. After standing several hours, the solution is warmed for one hour on the steam bath, allowing the alcohol to boil off. The residue is then taken up in ether and water, the ether layer separated and washed with 2% sodium hydroxide solution and finally with water. The washed ether solution is dried over solid potassium carbonate, and filtered. After acidifying with alcoholic hydrogen chloride, the ether is distilled off and the alcoholic residue diluted with an equal volume of acetone. The crystalline hydrochloride is filtered off, triturated with alcohol, diluted with several volumes of acetone, filtered and dried; MP 209°-210°C.
- brand name Camoform Hydrochloride (Parke-Davis).
- Therapeutic Function Antiamebic
bialamicol Preparation Products And Raw materials
Raw materials
Preparation Products
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493-75-4, bialamicolRelated Search:
- C28H40N2O2
- 比拉米可
- 493-75-4
- 3,3'-Bis[(diethylamino)methyl]-5,5'-di-2-propen-1-yl[1,1'-biphenyl]-4,4'-diol
- bialamicol USP/EP/BP
- [1,1'-Biphenyl]-4,4'-diol, 3,3'-bis[(diethylamino)methyl]-5,5'-di-2-propen-1-yl-
- bialamicol
- 2-allyl-4-[3-allyl-5-(diethylaminomethyl)-4-hydroxy-phenyl]-6-(diethylaminomethyl)phenol
- 2-(diethylaminomethyl)-4-[3-(diethylaminomethyl)-4-hydroxy-5-prop-2-enylphenyl]-6-prop-2-enylphenol
- 2-(diethylaminomethyl)-4-[3-(diethylaminomethyl)-4-hydroxy-5-prop-2-enyl-phenyl]-6-prop-2-enyl-phenol
- 5,5'-Diallyl-3,3'-bis[(diethylamino)methyl]-4,4'-dihydroxybiphenyl
- 5,5'-Bis(diethylaminomethyl)-3,3'-diallyl-1,1'-biphenyl-4,4'-diol
- 3,3-diallyl-5,5-bis(diethylaminomethyl)biphenyl-4,4-diol