ChemicalBook > CAS DataBase List > 1-Methyl-L-tryptophan

1-Methyl-L-tryptophan

CAS No.21339-55-9
Chemical Name:1-Methyl-L-tryptophan
CBNumber:CB6744979
Molecular Formula:C12H14N2O2
Formula Weight:218.25
MOL File:21339-55-9.mol

1-Methyl-L-tryptophan Property

Melting point >300 °C (dec.)(lit.)
Boiling point 429.3±35.0 °C(Predicted)
Density 1.28
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly, Sonicated), DMSO (Slightly）
form White to off-white powder.
pka 2.26±0.10(Predicted)
color Off-White to Pale Beige
optical activity [α]24/D 8.0°, c = 2 in acetic acid
FDA UNII XD0FY1J13B
UNSPSC Code 12352209
NACRES NA.22

Safety

Hazard Codes :Xn
Risk Statements :20/21/22
Safety Statements :36
WGK Germany :3
RTECS :YN7135000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302
Precautionary statements P501-P270-P264-P301+P312+P330

1-Methyl-L-tryptophan Price More Price(2)

Brand: Sigma-Aldrich(India)
Product number: 447439
Product name : 1-Methyl-L-tryptophan
Purity: 95%
Packaging: 1G
Price: ₹3940.3
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 447439
Product name : 1-Methyl-L-tryptophan
Purity: 95%
Packaging: 5G
Price: ₹12383.8
Updated: 2022/06/14
Buy: Buy

1-Methyl-L-tryptophan Chemical Properties,Usage,Production

Uses 1-Methyl-L-tryptophan can be used:
- In the preparation of L-tryptophan-based ligand for regioselective copper catalyzed N²-arylation of 1,2,3-triazoles.
- As a key starting material for the total synthesis of (?)-ardeemin.
- In the synthesis of cyclic peptide-capped gold nanoparticles as drug delivery systems.
Definition ChEBI: 1-methyl-L-tryptophan is an indolyl carboxylic acid.
reaction suitability reaction type: solution phase peptide synthesis

in vivo

(S)-Indoximod (5 mg/day, i.p. for 3 weeks) reverses the Bacillus Calmette-Guerin (BCG)-induced neurotoxicity in mice^[3].
(S)-Indoximod (200 mg/kg, oral gavage) shows delayed, lasts longer renoprotective effect than D isomer, and increases survival in the IRI rat model^[4].
(S)-Indoximod (1-9 mg/kg, i.p.) reverses cognitive, anxiety, and depressive-like behavior in bile duct ligation (BDL) rats^[5].

Animal Model:	Bile duct ligation (BDL) rats^[5]
Dosage:	1-9 mg/kg
Administration:	i.p., After the rats recovered for 7 days from BDL surgery.
Result:	Increased the sucrose preference. Prevents the increased number of buried marbles. Improved learning and memory function.

1-Methyl-L-tryptophan Preparation Products And Raw materials

Raw materials

Preparation Products

1-Methyl-L-tryptophan Suppliers

Global(190)Suppliers