ChemicalBook > CAS DataBase List > Trimethyl phosphonoacetate
Trimethyl phosphonoacetate
Trimethyl phosphonoacetate
- CAS No.5927-18-4
- Chemical Name:Trimethyl phosphonoacetate
- CBNumber:CB6726270
- Molecular Formula:C5H11O5P
- Formula Weight:182.11
- MOL File:5927-18-4.mol
Trimethyl phosphonoacetate Property
- Melting point 242 °C
- Boiling point 118 °C0.85 mm Hg(lit.)
- Density 1.125 g/mL at 25 °C(lit.)
- refractive index n
20/D 1.437(lit.) - Flash point >230 °F
- storage temp. Keep in dark place,Sealed in dry,Room Temperature
- form Liquid
- Specific Gravity approximate 1.265g/ml (20℃)
- color Clear colorless to light yellow
- Water Solubility Slightly miscible with water.
- BRN 1865177
- LogP -0.680 (est)
- CAS DataBase Reference 5927-18-4(CAS DataBase Reference)
- NIST Chemistry Reference Trimethyl phosphonoacetate(5927-18-4)
- EPA Substance Registry System Acetic acid, (dimethoxyphosphinyl)-, methyl ester (5927-18-4)
- UNSPSC Code 12352108
- NACRES NA.22
Safety
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H227-H315-H319-H335
- Precautionary statements P210e-P261-P280a-P305+P351+P338-P405-P501a
Trimethyl phosphonoacetate Price
More Price(9)
- Brand: Sigma-Aldrich(India)
- Product number: T79758
- Product name : Trimethyl phosphonoacetate
- Purity: 98%
- Packaging: 25G
- Price: ₹2717.08
- Updated: 2022/06/14
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- Brand: Sigma-Aldrich(India)
- Product number: T79758
- Product name : Trimethyl phosphonoacetate
- Purity: 98%
- Packaging: 100G
- Price: ₹8627.53
- Updated: 2022/06/14
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- Product number: ALF-A13301-36
- Product name : Trimethyl phosphonoacetate, 98%
- Purity:
- Packaging: 500g
- Price: ₹24562
- Updated: 2022/05/26
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- Brand: ALFA India
- Product number: ALF-A13301-22
- Product name : Trimethyl phosphonoacetate, 98%
- Purity:
- Packaging: 100g
- Price: ₹8355
- Updated: 2022/05/26
- Buy: Buy
- Brand: ALFA India
- Product number: ALF-A13301-14
- Product name : Trimethyl phosphonoacetate, 98%
- Purity:
- Packaging: 25g
- Price: ₹2880
- Updated: 2022/05/26
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Trimethyl phosphonoacetate Chemical Properties,Usage,Production
- Chemical Properties clear colorless to light yellow liquid
- Uses Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.
-
Application
Trimethyl phosphonoacetate is an important Wittig-horner reagent, which can be used to manufacture important intermediates of natural compounds such as vitamins, drugs, insect pheromones, etc.
Reactant involved in:
Intramolecular Mannich-type reactions to produce the sarain A diazatricyclic core
Organocatalytic oxa-Michael reactions
Prenylation and geranylation of oxindoles
Intramolecular Horner-Wadsworth-Emmons reactions
Olefin cross-metathesis / heterocyclization - Definition ChEBI: Trimethyl phosphonoacetate is a phosphonic ester.
- reaction suitability reaction type: C-C Bond Formation
Trimethyl phosphonoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
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- 5927-18-4
- Olefination
- Horner-Wadsworth-Emmons Reagents
- C-C Bond Formation
- Wittig & Horner-Emmons Reaction
- Synthetic Organic Chemistry
- Horner-Emmons Reaction
- 日用化工
- 医用原料
- 杂质对照品
- 化学试剂
- 抑制剂
- 合成材料中间体
- 其他化工中间体
- 高端化学
- 原料药
- 有机化学
- 化工原料
- 化工中间体
- 有机化工原料
- 原料
- 其他生化试剂
- 生化试剂
- 合成试剂
- 精细化学品
- 医药中间体
- 键形成
- 其他杂环
- 有机原料
- 香精香料
- 植物提取物
- C-C Bond Formation
- Horner-Emmons Reaction
- Wittig & Horner-Emmons Reaction
- Synthetic Reagents
- Olefination
- Horner-Wadsworth-Emmons Reagents
- C5H11O5P
- CH3O2POCH2CO2CH3
- 三甲基膦酰基乙酸酯/AR
- 化合物 TRIMETHYL PHOSPHONOACETATE
- 13C2,2H2]-(二甲氧基膦基)乙酸甲酯
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- 磷酰乙酸三甲酯
- 磷乙酸三甲酯
- 膦酰基乙酸三甲酯
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- 三甲基膦酰基乙酸
- 磷酸乙酸三甲酯,98%
- 膦酰乙酸三甲酯
- 磷酸乙酸三甲酯
- 三甲基膦酰基乙酸酯
- 三甲基膦酰基乙酸酯,95%
- 三甲基磷酸乙酯
- 磷酸乙酸三甲酯 1KG
- 5927-18-4