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AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH

AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Structure
AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH
  • CAS No.66641-26-7
  • Chemical Name:AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH
  • CBNumber:CB6477149
  • Molecular Formula:C87H125N21O21
  • Formula Weight:1801.05
  • MOL File:66641-26-7.mol
AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Property
  • Density 1.41±0.1 g/cm3(Predicted)
  • storage temp. −20°C
  • solubility insoluble in EtOH; insoluble in H2O; ≥180.1 mg/mL in DMSO
  • form solid
  • pka 2.98±0.10(Predicted)
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Chemical Properties,Usage,Production

  • Uses Acetyl angiotensinogen (1-14), porcine is a synthetic peptide and N-terminal acetylated form of Angiotensinogen (1-14) porcine (HY-P4774)[1].
  • Biological Activity acetyl angiotensinogen (1-14),porcine, (c87h125n21o21) is a peptide with the sequence ac-asp-arg-val-tyr-ile-his-pro-phe-his-leu-leu-val-tyr-ser-oh, mw= 1801.05. the protein encoded by the angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor. pre-angiotensinogen is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure(1). the resulting product, angiotensin i, is then cleaved by angiotensin converting enzyme (ace) to generate the physiologically active enzyme angiotensin ii. angiotensin ii is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia(2). mutations in the gene are associated with susceptibility to essential hypertension and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. defects in the gene have also been associated with non-familial structural atrial fibrillation and inflammatory bowel disease.figure1 formula of acetyl angiotensinogen (1-14),porcinefigure2 the renin–angiotensin–aldosterone system
  • References 1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9.2. Skurk T, Lee YM, Hauner H (May 2001). "Angiotensin II and its metabolites stimulate PAI-1 protein release from human adipocytes in primary culture". Hypertension 37 (5): 1336–40.
AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Preparation Products And Raw materials
Raw materials
Preparation Products
AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Suppliers
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AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Spectrum
66641-26-7, AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OHRelated Search:
  • SignalTransduction
  • 标准品
  • 多肽
  • Other Peptides
  • Peptides
  • BioChemical
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • C87H125N21O21
  • 乙酰血管紧张素原(1-14)ANGIOTENSINOGEN(1-14), PORCINE
  • 乙酰化猪源血管紧张素原片段多肽1-14
  • 肽ACETYL ANGIOTENSINOGEN (1-14)
  • 66641-26-7
  • Angiotensinogen (tetradecapeptide renin substrate), N-acetyl-5-L-isoleucine-
  • Acetyl-Preangiotensinogen (1-14) (horse), Acetyl-Tetradecapeptide Renin Substrate (horse), Acetyl-Angiotensinogen (1-14) (horse)
  • Ac-Angiotensinogen (1-14), porcine
  • Angiotensinogenn-acetyl-fragment1-14
  • ACETYL-PREANGIOTENSINOGEN (1-14) (HORSE)
  • ACETYL-TETRADECAPEPTIDE RENIN SUBSTRATE (HORSE)
  • ACETYL-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER
  • ACETYL ANGIOTENSINOGEN (1-14), PORCINE
  • ACETYL-ANGIOTENSINOGEN (1-14) (HORSE)
  • AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH
  • AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER
  • N-ACETYL-RENIN SUBSTRATE TETRADECAPEPTIDE PORCINE

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