ChemicalBook > CAS DataBase List > PSI-7977-13C-d3
PSI-7977-13C-d3
PSI-7977-13C-d3
- CAS No.2070009-25-3
- Chemical Name:PSI-7977-13C-d3
- CBNumber:CB64666758
- Molecular Formula:C22H26D3FN3O9P
- Formula Weight:533.46
- MOL File:2070009-25-3.mol
PSI-7977-13C-d3 Property
- Density 1.413±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- storage temp. Store at -20°C
- solubility DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml
- form A solid
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
PSI-7977-13C-d3 Chemical Properties,Usage,Production
- Description PSI-7977-13C-d3 is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo.
- Uses PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
PSI-7977-13C-d3 Preparation Products And Raw materials
Raw materials
Preparation Products
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2070009-25-3, PSI-7977-13C-d3Related Search:
- Sofosbuvir IMpurity ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-Methyltetrahydrofuran-2-yl)Methyl benzoate Sofosbuvir Impurity 8 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) Sofosbuvir alpha-D-erythro-Pentofuranous-2-ulose 1,3,5-tribenzoate Sofosbuvir Impurity 19 PSI 352707-13C,D3 PSI-7976 Sofosbuvir D6 Sofosbuvir Impurity Sofosbuvir metabolites GS566500 Sofosbuvir metabolites PSI 7411 Sofosbuvir Impurity 32 PSI-6206 13CD3 (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
- C2113CH26D3FN3O9P
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- 2070009-25-3
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- PSI-7977-13C-d3
- Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
- isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
- [13C,2H3]-Sofosbuvir