ChemicalBook > CAS DataBase List > PSI-7976
PSI-7976
PSI-7976
- CAS No.1190308-01-0
- Chemical Name:PSI-7976
- CBNumber:CB42685935
- Molecular Formula:C22H29FN3O9P
- Formula Weight:529.45
- MOL File:1190308-01-0.mol
PSI-7976 Property
- Melting point 76-82°C
- Density 1.41±0.1 g/cm3(Predicted)
- storage temp. -20°C Freezer
- solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly)
- pka 9.39±0.10(Predicted)
- form Solid
- color White to Off-White
- FDA UNII V14CN8M621
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P305+P351+P338
PSI-7976 Chemical Properties,Usage,Production
- Uses Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
PSI-7976 Preparation Products And Raw materials
Raw materials
Preparation Products
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1190308-01-0, PSI-7976Related Search:
- GAMMA-CYHALOTHRIN Sofosbuvir metabolites Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) PSI-7977-13C-d3 Sofosbuvir SofosBuvir impurity 45 SofosBuvir Impurity 53 sofosBuvir Impurity 37 PSI 7411 Sofosbuvir Impurity 6 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Sofosbuvir Impurity27 SofosBuvir Impurity 38 Sofosbuvir impurity I (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate Sofosbuvir impurity D SofosBuvir Impurity 31 sofosBuvir Impurity 33
- 杂质对照品
- 对照品-杂质对照品
- 索非布韦杂质
- 190308-01-0
- (R)-(((2R,3R,4R,5R)-L-索非布韦异构体(索非布韦国际药典杂质A)
- 索非司布韦国际药典杂质A
- 索非布韦杂质(异构体)
- 化合物 T12956L
- 索福斯布韦杂质A
- Y008005-A
- 索非布韦R-磷酸盐
- 索氟布韦杂质6
- PSI-7976/ PSI7977杂质A
- 索非布韦杂质19
- 索非布韦杂质01
- 磷异构体
- 1190308-01-0
- (R)-(((2R,3R,4R,5R)-L-Sofosbuvir Isomer(Sofosbuvir INT Impurity A)
- SFB-L-ALANITE-MODEL
- isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate
- L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester
- isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite
- Sofosbuvir impurity 14/ RP-Isomer of Sofosbuvir/Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
- Sofosbuvir phosphate salt
- SFB-L-Alaninate-Model
- Sofosbuvir L-alanitate (Mixture of Diasteriomers)Q: What is Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the CAS Number of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the storage condition of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What are the applications of Sofosbuvir L-alanitate (Mixture of Diasteriomers)
- (S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate
- Sofosbuvir (R)-Phosphate
- N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester
- PSI-7976