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L-NORADRENALINE BITARTRATE

L-NORADRENALINE BITARTRATE Structure
L-NORADRENALINE BITARTRATE
  • CAS No.51-40-1
  • Chemical Name:L-NORADRENALINE BITARTRATE
  • CBNumber:CB6417136
  • Molecular Formula:C8H11NO3.C4H6O6
  • Formula Weight:319.26
  • MOL File:51-40-1.mol
L-NORADRENALINE BITARTRATE Property
  • storage temp. Store at 4°C, protect from light
  • solubility 31.93mg/mL in DMSO
  • pka 8.64(at 25℃)
  • Melting point 102-104 °C
  • Water Solubility 31.93mg/mL in Water
  • CAS DataBase Reference 51-40-1(CAS DataBase Reference)
  • FDA UNII ZW81GF408B
Safety
  • RIDADR  :3249
  • HazardClass  :6.1(b)
  • PackingGroup  :III
  • Toxicity :LD50 ivn-rat: 210 mg/kg YACHDS 7,627,79
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H360-H300-H330-H310
  • Precautionary statements P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501

L-NORADRENALINE BITARTRATE Chemical Properties,Usage,Production

  • Uses Adrenergic (vasoconstrictor).
  • brand name Levophed (Hospira).
  • Clinical Use
    Hypotension
    Cardiac arrest (sympathomimetic)
  • Safety Profile Poison by intravenous andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.
  • Drug interactions Potentially hazardous interactions with other drugs
    Adrenergic neurone blockers: antagonise hypotensive effect.

    Anaesthetics: increased risk of arrhythmias with volatile general anaesthetics.

    Antidepressants: tricyclics may cause hypertension and arrhythmias; MAOIs and moclobemide may cause hypertensive crisis.

    Beta-blockers: can cause severe hypertension.
    Clonidine: possibly increased risk of hypertension.

    Dopaminergics: effects possibly increased by entacapone; avoid with rasagiline.

    Sympathomimetics: effects possibly enhanced by dopexamine.
  • Metabolism Extensively metabolised by catechol-O-methyltransferase (COMT), and monoamine oxidase (MAO).
    Up to 16% of an intravenous dose is excreted unchanged in the urine with methylated and deaminated metabolites in free and conjugated forms.
  • storage Store at +4°C
L-NORADRENALINE BITARTRATE Preparation Products And Raw materials
Raw materials
Preparation Products
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L-NORADRENALINE BITARTRATE Spectrum
51-40-1, L-NORADRENALINE BITARTRATERelated Search:
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