Felodipine

Felodipine Property

Safety

Hazard and Precautionary Statements (GHS)

Felodipine Chemical Properties,Usage,Production

Uses Vasodilator.
brand name Plendil (AstraZeneca).
Clinical Use Calcium-channel blocker:
Hypertension
Angina
Drug interactions Potentially hazardous interactions with other drugs
Aminophylline and theophylline: possibly increased aminophylline and theophylline concentration.
Anaesthetics: enhanced hypotensive effect.
Antibacterials metabolism possibly inhibited by clarithromycin, erythromycin and telithromycin.
Antidepressants: enhanced hypotensive effect with MAOIs.
Antiepileptics: effect reduced by carbamazepine, barbiturates, phenytoin and primidone.
Antifungals: metabolism inhibited by itraconazole and ketoconazole; negative inotropic effect possibly increased with itraconazole.
Antihypertensives: enhanced hypotensive effect, increased risk of first dose hypotensive effect of postsynaptic alpha-blockers.
Antivirals: concentration possibly increased by ritonavir; use with caution with telaprevir.
Grapefruit juice: concentration increased - avoid concomitant use.
Tacrolimus: possibly increased tacrolimus concentration
Metabolism Felodipine is metabolised in the liver and all identified metabolites are devoid of vasodilating properties. Approximately 70% of a given dose is excreted as metabolites in the urine and about 10% with the faeces. Less than 0.5% of the dose is excreted unchanged in the urin

Felodipine Preparation Products And Raw materials

Raw materials

Preparation Products

Felodipine Suppliers

Global(207)Suppliers

Felodipine Spectrum

86189-69-7, FelodipineRelated Search:

化学试剂
医用原料
杂质对照品
对照品-杂质对照品
医药选择性钙离子拮抗药
原料药
医药、农药及染料中间体
医药原料药
心脑血管和血液
抗生素类
医药原料
抗高血压
原料
Voltage-gated Ion Channels
Ion Channels
Inhibitors and Activators
BioChemical
Calcium Channel Modulators
Cell Signaling and Neuroscience
Cell Biology
4-(2,3-二氯苯基)-1,4-二氢-2,6-二甲基-3,5-吡啶二羧酸乙基甲基酯
非洛地平杂质
非洛地平
非洛地平杂质(3个)
86189-69-7
FELODIPINE USP, NON-STERILE DRUG SUBSTANCE
Felodipine Powder USP Standard
5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1
Perfudal
Perfuda
5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Felodipine Imp
Felodipine iMpurity
3-ethyl 5-Methyl (4R)-4-(2,3-dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylate
Felodipina
Brn 4331472
Agon sr
ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
FELODAY
FLODIL
4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID METHYL ESTER
4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINECARBOXYLIC ACID METHYL ESTER