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13(R)-HODE

13(R)-HODE Structure
13(R)-HODE
  • CAS No.10219-69-9
  • Chemical Name:13(R)-HODE
  • CBNumber:CB6395450
  • Molecular Formula:C18H32O3
  • Formula Weight:296.44
  • MOL File:10219-69-9.mol
13(R)-HODE Property
  • Boiling point 422.7±20.0 °C(Predicted)
  • Density 0.970±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
  • pka 4.78±0.10(Predicted)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H319
  • Precautionary statements P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501

13(R)-HODE Chemical Properties,Usage,Production

  • Description 13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50 = 2.7 μM) inhibitor of U-46619-induced platelet aggregation.2
  • Uses 13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50=2.7 μM) inhibitor of U-46619-induced platelet aggregation.
  • Definition ChEBI: 13(R)-HODE is a 13-HODE in which the stereocentre at position 13 has S-configuration. It is a conjugate acid of a 13(R)-HODE(1-).
  • References 1. Baer, A.N., Costello, P.B., and Green, F.A. Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells Biochim. Biophys. Acta 1085(1),45-52(1991).
    2. Lagarde, M., Boutillon, M.M., Guichardant, M., et al. Further studies on the anti-thromboxane A2 activity of monohydroxylated fatty acids Biochem. Pharmacol. 38,1863-1864(1989).
13(R)-HODE Preparation Products And Raw materials
Raw materials
Preparation Products
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13(R)-HODE Spectrum
10219-69-9, 13(R)-HODERelated Search:
  • 抑制剂
  • 10219-69-9
  • 13(R) HODE,13(R)HODE
  • 9,11-Octadecadienoic acid, 13-hydroxy-, (9Z,11E,13R)-
  • HNICUWMFWZBIFP-PIHGWCCBSA-N
  • 13(R)-hydroxy-9,11-octadienoic acid
  • 9,11-Octadecadienoic acid, 13-hydroxy-, (R-(E,Z))-
  • (R-(E,Z))-13-Hydroxy-9,11-octadecadienoic acid
  • Coriolic acid
  • (R,9Z,11E)-13-Hydroxy-9,11-octadecadienoic acid
  • 13R-HYDROXY-9Z,11E-OCTADECADIENOIC ACID
  • 13(R)-HODE

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