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o-Cresolphthalein

CAS No.596-27-0
Chemical Name:o-Cresolphthalein
CBNumber:CB6392671
Molecular Formula:C22H18O4
Formula Weight:346.38
MOL File:596-27-0.mol

o-Cresolphthalein Property

Melting point 223-225 °C
Boiling point 401.12°C (rough estimate)
Density 1.1425 (rough estimate)
refractive index 1.4400 (estimate)
storage temp. room temp
solubility Solubility Slightly soluble in water; soluble in ethanol
form powder
pka 9.40(at 25℃)
color Clear colorless
PH Range 8.2 (colorless) - 9.8 (violet/red)
PH 8.2-9.8, colorless to red
Water Solubility slightly soluble
λmax 566nm, 381nm
ε(extinction coefficient) ≥10000 at 294-300nm
≥39000 at 564-570nm
≥5000 at 378-384nm
Merck 14,2576
BRN 310554
Major Application Sensors, display device, photoresists, recording materials, imaging materials, authentication system for secure documents, decoder system, lithium cells, electroplating process, inks, markers, toners, correction fluid, paints, adhesives, floor coatings, gas leaking detector for safety in industries, toys, food storage, diapers, determination of calcium, lotions, urine analysis test strips, drugs, blood analysis
InChIKey CPBJMKMKNCRKQB-UHFFFAOYSA-N
CAS DataBase Reference 596-27-0(CAS DataBase Reference)
FDA UNII XOU2D9049G
EPA Substance Registry System 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3-methylphenyl)- (596-27-0)
UNSPSC Code 12171500
NACRES NA.47

Safety

Hazard Codes :Xn
Risk Statements :40-36/37/38-20/21/22
Safety Statements :36/37-36-26
RIDADR :1170
WGK Germany :3
RTECS :SM8390000
TSCA :Yes
HS Code :3822.19.0080

NFPA 704:

	0
1		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H225-H319-H335+H336-H340-H360-H372-H373
Precautionary statements P201-P202-P210-P233-P240-P241+P242+P243-P260-P264-P270-P271-P280-P303+P361+P353-P304+P340+P312-P305+P351+P338+P337+P313-P308+P313-P403+P233-P405-P501

o-Cresolphthalein Price More Price(6)

Brand: Sigma-Aldrich(India)
Product number: C85778
Product name : o-Cresolphthalein
Purity: indicator grade
Packaging: 10G
Price: ₹4817.13
Updated: 2022/06/14
Buy: Buy

Brand: TCI Chemicals (India)
Product number: C0404
Product name : o-Cresolphthalein
Purity:
Packaging: 25G
Price: ₹3500
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: C0404
Product name : o-Cresolphthalein
Purity:
Packaging: 100G
Price: ₹9100
Updated: 2022/05/26
Buy: Buy

Brand: SRL
Product number: 29121
Product name : o-Cresolphthalein AR, 95%
Purity:
Packaging: 5Gms
Price: ₹160
Updated: 2022/05/26
Buy: Buy

Brand: SRL
Product number: 29121
Product name : o-Cresolphthalein AR, 95%
Purity:
Packaging: 25Gms
Price: ₹580
Updated: 2022/05/26
Buy: Buy

o-Cresolphthalein Chemical Properties,Usage,Production

Chemical Properties white to pink or beige to tan powder. soluble in ethanol, ether, glacial acetic acid, soluble in dilute alkali and turns purple, slightly soluble in water, hardly soluble in benzene.
Uses O-Cresolphthalein has been used as a component in calcifying media for calcification assay. It is also used as an indicator (pH range, 8.2 colorless, 9.8 red) and analytical reagent.
Application O-Cresolphthalein is a gadolinium chelate that is used as a contrast agent for magnetic resonance imaging (MRI) of the brain, spine, and joints. The gadolinium ion is bound to the cresol molecule, which has an attached hydroxyl group. This complex attaches to the phosphorous pentoxide and creates a precipitate of metal hydroxides in the presence of water and sodium carbonate. O-Cresolphthalein is also used in clinical pathology to measure glomerular filtration rate (GFR), which is important for diagnosing renal disease. MRI scans are used to diagnose osteogenic genes that are associated with bone diseases such as osteoporosis.
Biochem/physiol Actions o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.