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TCID
TCID
- CAS No.30675-13-9
- Chemical Name:TCID
- CBNumber:CB6366908
- Molecular Formula:C9H2Cl4O2
- Formula Weight:283.92
- MOL File:30675-13-9.mol
TCID Property
- Melting point 218-220
- Boiling point 448.1±45.0 °C(Predicted)
- Density 1.782±0.06 g/cm3(Predicted)
- storage temp. +2C to +8C
- solubility Soluble in DMSO (up to 25 mg/ml),
- form Orange solid
- pka 8.62±0.20(Predicted)
- color White
- Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
- UNSPSC Code 12352200
- NACRES NA.77
Safety
- Hazard Codes :Xi
- Hazard Note :Irritant
-
NFPA 704:
0 2 0
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302
- Precautionary statements P280-P305+P351+P338
TCID Chemical Properties,Usage,Production
- Description TCID (30675-13-9) inhibits ubiquitin C-terminal hydrolase L3 (UCH-L3). IC50=0.6 μM, 125-fold selective over UCH-L1, IC50=75 μM. Cell permeable.
- Uses TCID is a small molecule inhibitor of DNA polymerase λ.
- storage Store at -20°C
- References 1) Love et al. (2007), Mechanisms, biology and inhibitors of deubiquitinating enzymes; Nat. Chem. Biol., 3 697 2) Mtango et al. (2012), Essential role of ubiquitin C-terminal hydrolases UCHL1 and UCHL3 in mammalian oocyte maturation; J. Cell Physiol., 227 2022
TCID Preparation Products And Raw materials
Raw materials
Preparation Products
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30675-13-9, TCIDRelated Search:
- Ninhydrin hydrate Ninhydrine, ozone friendly ready to use spray for TLC chromatography BINDONE DIPHACINONE 2-NITRO-1,3-INDANDIONE 2-ISOVALERYL-1,3-INDANEDIONE 2-BENZOYL-1,3-INDANEDIONE Bromindione 2-(DICYANOMETHYLENE)INDAN-1,3-DIONE PINDONE 2-PHENYL-1,3-INDANDIONE Solvent Yellow 33 HYDRINDANTIN Disperse Yellow 64 Chlorophacinone Indan 1,3-Indanedione 2-((4-CHLOROPHENYL)METHYLENE)INDANE-1,3-DIONE
- Inhibitors
- 化工
- 抑制剂
- 合成有机化合物配体
- 中药对照品
- 小分子抑制剂,天然产物
- C9H2Cl4O2
- 化合物TCID,10 MM DMSO 溶液
- 4,5,6,7-四氯-1H-茚-1,3(2H)-二酮
- TCID,泛素C末端水解酶L3抑制剂
- 4,5,6,7-四氯茚满-1,3-二酮
- 30675-13-9
- TCID, 10 mM in DMSO
- hydrolase,C-terminal,Neuronal,Deubiquitinase,transporter,ubiquitination,DUBs,inhibit,TCID,glycine,ubiquitin,UCH-L3,UCH-L1,GlyT2,Inhibitor
- TCID USP/EP/BP
- TCID >=98% (HPLC)
- UCH-L3 Inhibitor - CAS 30675-13-9 - Calbiochem
- UCH-L3 Inhibitor
- 4,5,6,7-Tetrachloroindane-1,3-dione 4,5,6,7-Tetrachloroindan-1,3-dione
- 1H-Indene-1,3(2H)-dione, 4,5,6,7-tetrachloro-
- TCID
- 4,5,6,7-tetrachloro-2,3-dihydro-1H-indene-1,3-dione
- 4,5,6,7-Tetrachloroindane-1,3-dione 95+%
- 4,5,6,7-Tetrachloro-1,3-indanedione
- 4,5,6,7-TETRACHLORO-1H-INDENE-1,3(2H)-DIONE
- 4,5,6,7-TETRACHLOROINDANE-1,3-DIONE
- 4,5,6,7-TETRACHLOROINDAN-1,3-DIONE