ChemicalBook > CAS DataBase List > Fluorescein-PEG6-Acid
Fluorescein-PEG6-Acid
Fluorescein-PEG6-Acid
- CAS No.2055014-69-0
- Chemical Name:Fluorescein-PEG6-Acid
- CBNumber:CB63162947
- Molecular Formula:C36H42N2O13S
- Formula Weight:742.79
- MOL File:2055014-69-0.mol
Fluorescein-PEG6-Acid Property
- Boiling point 917.7±75.0 °C(Predicted)
- Density 1.44±0.1 g/cm3(Predicted)
- solubility Soluble in Water, DMSO, DMF, DCM
- pka 4.28±0.10(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Fluorescein-PEG6-Acid Chemical Properties,Usage,Production
- Description Fluorescein-PEG6-Acid is a xanthene dye with excitation/emmission maximum 494/517 nm and a free terminal carboxyl acid. Terminal carboxylic acid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. It be used as quantum yield standard. Hydophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding.
- Uses Fluorescein-thiourea-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- IC 50 PEGs
- References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fluorescein-PEG6-Acid Preparation Products And Raw materials
Raw materials
Preparation Products
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2055014-69-0, Fluorescein-PEG6-AcidRelated Search:
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