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Fluorescein-PEG4-Acid

Fluorescein-PEG4-Acid Structure
Fluorescein-PEG4-Acid
  • CAS No.1807518-76-8
  • Chemical Name:Fluorescein-PEG4-Acid
  • CBNumber:CB63062498
  • Molecular Formula:C32H34N2O11S
  • Formula Weight:654.68
  • MOL File:1807518-76-8.mol
Fluorescein-PEG4-Acid Property
  • Boiling point 873.4±75.0 °C(Predicted)
  • Density 1.49±0.1 g/cm3(Predicted)
  • solubility Soluble in Water, DMSO, DMF, DCM
  • pka 4.28±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Fluorescein-PEG4-Acid Chemical Properties,Usage,Production

  • Description Fluorescein-PEG4-Acid is a xanthene dye with excitation/emmission maximum 494/517 nm and a free terminal carboxyl acid. Terminal carboxylic acid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. It be used as quantum yield standard. Hydophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding.
  • Uses Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fluorescein-PEG4-Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Fluorescein-PEG4-Acid Suppliers
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Fluorescein-PEG4-Acid Spectrum
1807518-76-8, Fluorescein-PEG4-AcidRelated Search:
  • 化学试剂
  • C32H34N2O11S
  • 1-((3',6'-二羟基-3-氧代-3H-螺[异苯并呋喃-1,9'-氧杂蒽]-5-基)氨基)-1-硫代-5,8,11,14-四氧杂-2-氮杂十七烷-17-酸
  • 1-((3',6'-二羟基-3-氧代-3H-螺[异苯并呋喃-1,9'-氧杂蒽]-5-基)氨基)-1-硫代-5,8,11,14-四氧杂-2-氮杂十七烷-17-酸
  • 4,7,10,13-四氧化乙酸,17-[(3',6'-二羟基-3-氧化氢[异呋喃-1(3H),9'-[9H]XANTHEN]-5-Y1)氨基]-17-硫代-
  • 荧光素聚乙二醇-4-酸
  • 5-异硫氰酸荧光素-四聚乙二醇-羧基
  • 5-FITC-四聚乙二醇-羧基
  • 荧光素-四聚乙二醇-丙酸
  • 1807518-76-8
  • 1-((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)amino)-1-thioxo-5,8,11,14-tetraoxa-2-azaheptadecan-17-oic acid
  • 1-((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)amino)-1-thioxo-5,8,11,14-tetraoxa-2-azaheptadecan-17-oic acid
  • 4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-17-thioxo-
  • Flurescein-PEG4-COOH
  • 5-FITC-PEG4-COOH
  • Fluorescein-PEG4-Acid

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