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Phthalic acid

CAS No.88-99-3
Chemical Name:Phthalic acid
CBNumber:CB6289456
Molecular Formula:C8H6O4
Formula Weight:166.13
MOL File:88-99-3.mol

Phthalic acid Property

Melting point 210-211 °C (dec.) (lit.)
Boiling point 214.32°C (rough estimate)
Density 1.59 g/cm3 at 15 °C
bulk density 960kg/m3
vapor pressure 7.8 hPa (191 °C)
refractive index 1.5100 (estimate)
Flash point 168 °C
storage temp. Store below +30°C.
solubility methanol: 0.1 g/mL, clear
form Powder
pka 2.89(at 25℃)
color White
PH 3.2(1 mM solution);2.55(10 mM solution);2(100 mM solution);
Water Solubility 7 g/L (25 ºC)
Merck 14,7371
BRN 608199
Dielectric constant 5.1（Ambient）
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey XNGIFLGASWRNHJ-UHFFFAOYSA-N
LogP 0.73 at 20℃
Indirect Additives used in Food Contact Substances O-PHTHALIC ACID
FDA 21 CFR 175.105
CAS DataBase Reference 88-99-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 6O7F7IX66E
NIST Chemistry Reference 1,2-Benzenedicarboxylic acid(88-99-3)
EPA Substance Registry System Phthalic acid (88-99-3)
UNSPSC Code 85151701
NACRES NA.24

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36-37/39
WGK Germany :1
RTECS :TH9625000
TSCA :Yes
HS Code :29173980
Hazardous Substances Data :88-99-3(Hazardous Substances Data)
Toxicity :LD50 orally in rats: 7.9 g/kg (Shaffer)

NFPA 704:

	1
1		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338

Phthalic acid Price More Price(20)

Brand: Sigma-Aldrich(India)
Product number: P39303
Product name : Phthalic acid
Purity: reagent grade, 98%
Packaging: 100G
Price: ₹4330
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: P39303
Product name : Phthalic acid
Purity: reagent grade, 98%
Packaging: 1KG
Price: ₹4416.6
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 80010
Product name : Phthalic acid
Purity: puriss. p.a., ≥99.5% (T)
Packaging: 100G
Price: ₹2478.93
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 80010
Product name : Phthalic acid
Purity: puriss. p.a., ≥99.5% (T)
Packaging: 1KG
Price: ₹7923.9
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 8.22298
Product name : Phthalic acid
Purity: for synthesis
Packaging: 100G
Price: ₹7980
Updated: 2022/06/14
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Phthalic acid Chemical Properties,Usage,Production

Description Phthalic acid is an aromatic dicarboxylic acid, with formula C₆H₄(CO₂H)₂. It is an isomer of isophthalic acid and terephthalic acid. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale.
Chemical Properties PHTHALIC ACID,C6H4(COOH)2, mp 208 °C (ortho), 330 °C (meta and iso), the ortho form sublimes and the meta and iso forms decompose with heat, sp gr 1.593 (ortho). Phthalic acid is very slightly soluble in H2O, soluble in alcohol, and slightly soluble in ether. The solid form is colorless, crystalline
Uses It is a dibasic acid, with pKa's of 2.89 and 5.51. The mono potassium salt, potassium hydrogen phthalate is a standard acid in analytical chemistry. Typically phthalate esters are prepared from the widely available phthalic anhydride. Reduction of phthalic acid with sodium amalgam in the presence of water gives the 1,3- cyclohexadiene derivative.
Uses Phthalic Acid (Phenyl-13C6, D4) is labelled Phthalic Acid (P384480) which is an organic reagent used to synthesize phthalates.
Definition ChEBI: A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.
Production Methods Phthalic acid is produced by the catalytic oxidation of naphthalene directly to phthalic anhydride and a subsequent hydrolysis of the anhydride.
Phthalic acid was first obtained by French chemist Auguste Laurent in 1836 by oxidizing naphthalene tetrachloride. Believing the resulting substance to be a naphthalene derivative, he named it "naphthalic acid". After the Swiss chemist Jean Charles Galissard de Marignac determined its correct formula, Laurent gave it its present name. Manufacturing methods in the nineteenth century included oxidation of naphthalene tetrachloride with nitric acid, or, better, oxidation of the hydrocarbon with fuming sulfuric acid, using mercury or mercury(II) sulfate as a catalyst.
Definition phthalic acid: colourlesscrystalline dicarboxylic acid,C₆H₄(COOH)₂; r.d. 1.6; m.p. 207°C.The two –COOH groups are substitutedon adjacent carbon atoms ofthe ring, the technical name beingbenzene-1,2-dicarboxylic acid. Theacid is made from phthalic anhydride(benzene-1,2-dicarboxylic anhydride,C₈H₄O₃), which is made by the catalyticoxidation of naphthalene. Theanhydride is used in making plasticizersand polyester resins.
Synthesis Reference(s) The Journal of Organic Chemistry, 30, p. 2414, 1965 DOI: 10.1021/jo01018a074
General Description White crystals or fine white powder.
Air & Water Reactions Insoluble in water.
Reactivity Profile Phthalic acid is a carboxylic acid. Phthalic acid is sensitive to exposure to extreme heat. Phthalic acid reacts violently with nitric acid. Phthalic acid is incompatible with sodium nitrite. Phthalic acid is also incompatible with oxidizers. .
Fire Hazard Phthalic acid is combustible.
Flammability and Explosibility Not classified
Safety Profile Moderately toxic by ingestion and intraperitoneal routes. A skin and mucous membrane irritant. Combustible when heated. In the form of dust (anhydride) it can explode. Mixtures with sodmm nitrite explode when heated. Violent reaction with HNO3. When heated to decomposition it emits acrid smoke and irritating fumes. Used in synthesis of dyes and dyestuffs, in medcines and perfumes.
Safety The toxicity of phthalic acid is low with LD₅₀ (mouse) of 550 mg/kg. However, many phthalate esters have been implicated as endocrine disruptors.
Purification Methods Crystallise phthalic acid from water. [Beilstein 9 IV 3167.]
Isomers Phthalic acid is one of three isomers of benzene dicarboxylic acid, the others being iso phthalic acid and terephthalic acid. Sometimes the term "phthalic acids" is used to refer to this family of isomers, but in the singular, "phthalic acid", refers exclusively to the ortho- isomer.