ChemicalBook > CAS DataBase List > H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH
H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH
H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH
- CAS No.118068-30-7
- Chemical Name:H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH
- CBNumber:CB6246837
- Molecular Formula:C43H68N12O16
- Formula Weight:1009.07
- MOL File:118068-30-7.mol
H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH Property
- storage temp. −20°C
- form solid
Safety
- Safety Statements :22-24/25
- WGK Germany :3
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH Chemical Properties,Usage,Production
- Uses Amylin (20-29) (human) is the fragment of human islet amyloid polypeptide (hIAPP) or Amylin. Amylin is a 37-residue hormone. Amylin (20-29) (human) is responsible for the amyloidogenic propensities of the full length protein. Amylin (20-29) (human) can be transformed into its corresponding peptoid and retropeptoid sequences, to obtain beta-sheet breaker peptides as amyloid inhibitors[1][2].
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References
[1] Kapurniotu A, et al. Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity. J Mol Biol. 2002 Jan 18;315(3):339-50. DOI:10.1006/jmbi.2001.5244
[2] Elgersma RC, et al. Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1837-42. DOI:10.1016/j.bmcl.2007.01.042
H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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118068-30-7, H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OHRelated Search:
- peptide
- 多肽
- Obesity Peptides
- Peptides
- BioChemical
- Amylins
- Amino Acids and Peptides
- Biochemicals and Reagents
- C43H68N12O16
- 胰淀素(20-29)(人)
- 人胰淀素(淀粉样肽)20-29
- 胰岛淀粉样多肽(20-29)(人类)
- 118068-30-7
- (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino ]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]
- Amylin (20-29), human - 1 mg
- H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH USP/EP/BP
- L-Serine, L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-
- Amylin (20-29) (human) H-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-OH
- diabetes associated peptide fragment 20-29 human
- SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER
- SNNFGAILSS
- AMYLIN (20-29) (HUMAN)
- AMYLIN (20-29)
- AMYLIN FRAGMENT 20-29 HUMAN
- H-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-OH