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(+)-AJ 76 HYDROCHLORIDE

(+)-AJ 76 HYDROCHLORIDE Structure
(+)-AJ 76 HYDROCHLORIDE
  • CAS No.85379-09-5
  • Chemical Name:(+)-AJ 76 HYDROCHLORIDE
  • CBNumber:CB6241438
  • Molecular Formula:C15H23NO
  • Formula Weight:233.35
  • MOL File:85379-09-5.mol
(+)-AJ 76 HYDROCHLORIDE Property
  • Boiling point 345.3±42.0 °C(Predicted)
  • Density 1.00±0.1 g/cm3(Predicted)
  • storage temp. Store at RT
  • solubility Soluble to 10 mM in H2O
  • form White crystalline solid.
  • pka 10.28±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

(+)-AJ 76 HYDROCHLORIDE Chemical Properties,Usage,Production

  • Uses (+)-AJ 76 Hydrochloride was used in asymmetric synthesis of methoxymethyl(di-n-propylamino)tetralin hydrochloride.
  • Definition ChEBI: A secondary amino compound that consists of tetralin bearing methyl, propylamino and methoxy groups at positions 1, 2 and 5 respectively. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 nd 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively).
  • Biological Activity Dopamine receptor antagonist with preferential action at presynaptic receptors (pK i values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD 3 . hD 4 , hD 2S , hD 2L and rD 2 receptors respectively).
  • References [1]. kullingsjö h, carlsson a, svensson k. effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)-aj76, on locomotor activity and brain da metabolism in the rat. eur j pharmacol, 1991, 205(3): 241-246.
    [2]. piercey mf, lum jt, hoffmann we, et al. antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-aj76 and (+)-uh232. brain res, 1992; 588(2): 217-222.
    [3]. waters n, hansson l, löfberg l, et al. intracerebral infusion of (+)-aj76 and (+)-uh232: effects on dopamine release and metabolism in vivo. eur j pharmacol, 1994, 251(2-3): 181-190.
(+)-AJ 76 HYDROCHLORIDE Preparation Products And Raw materials
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(+)-AJ 76 HYDROCHLORIDE Spectrum
85379-09-5, (+)-AJ 76 HYDROCHLORIDERelated Search:
  • (1S,2R)-顺-5-甲氧基-1-甲基-2-(N-丙胺)萘满盐酸盐
  • (+)-AJ 76盐酸盐
  • 85379-09-5
  • (+)-AJ 76
  • (1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine
  • 2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-1-methyl-N-propyl-, (1S,2R)-
  • (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin
  • U-80278A
  • N-Propyl-1α-methyl-5-methoxytetralin-2α-amine
  • (1S,2R)-1,2,3,4-Tetrahydro-5-methoxy-1-methyl-N-propyl-2-naphthalenamine
  • (1S)-1,2,3,4-Tetrahydro-5-methoxy-1α-methyl-N-propyl-2α-naphthalenamine
  • 5-methoxy-1-methyl-2-(n-propylamino)tetralin
  • (1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralinehydrochloride
  • (1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)TETRALIN HYDROCHLORIDE
  • (1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)-TETRALIN HCL
  • (+)-AJ 76 HYDROCHLORIDE
  • (+)-AJ76 HCL
  • AJ-76

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