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6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID

6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Structure
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID
  • CAS No.33458-93-4
  • Chemical Name:6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID
  • CBNumber:CB6209962
  • Molecular Formula:C17H14O5
  • Formula Weight:298.29
  • MOL File:33458-93-4.mol
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Property
  • storage temp. Sealed in dry,Room Temperature
  • solubility ethanol: 2.5 mg/mL, soluble
  • form crystalline solid or supercooled liquid
  • color White
  • Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months.
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: A1221
  • Product name : AH6809
  • Purity: ≥98%, crystalline solid or supercooled liquid
  • Packaging: 5MG
  • Price: ₹12925.05
  • Updated: 2022/06/14
  • Buy: Buy

6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

  • Description AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors. AH 6809 blocks the PGE2-induced accumulation of cAMP in COS cells transfected with the human EP2 receptor. It also blocks the accumulation of Ca2+ in Xenopus oocytes expressing the human EP1 receptor. In the human and guinea pig, the activity profile of AH 6809 is similar to that of SC-19220, but it is somewhat more potent. In the mouse, AH 6809 has the highest affinity for the EP2 receptor, but also acts as a weak ligand at the murine EP1 and DP1 receptors. In whole human platelets, AH 6809 is an effective antagonist of the antiaggregatory actions of PGD2, but not PGI2, with an EC50 of about 5 x 10−5 M.
  • Uses AH-6809 is a prostaglandin E2 receptor antagonist.
  • Definition ChEBI: 9-oxo-6-propan-2-yloxy-2-xanthenecarboxylic acid is a member of xanthones.
  • Biological Activity Antagonist at prostaglandin EP 1 (pA 2 = 6.8 ) and EP 2 (K i = 350 nM) receptors. Also weakly inhibits DP receptors (pA 2 = 4.45).
  • storage Store at RT
  • References 1) Coleman in Prostaglandins and Related Substances: A Practical Approach; ILR Press, Oxford and Washington D.C. 1987, pg 267
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Suppliers
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6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Spectrum
33458-93-4, 6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACIDRelated Search:
  • 抑制剂
  • 合成有机化合物配体
  • 6-异丙氧基-9-氧代氧杂蒽-2-羧酸,10 MM DMSO 溶液
  • AH 6809,EP1 AND EP2拮抗剂
  • AH 6809,EP1和EP2拮抗剂
  • 6-异丙氧基-9-氧杂蒽酮-2-羧酸
  • 6-异丙氧基-9-氧代氧杂蒽-2-羧酸
  • 33458-93-4
  • AH 6809, 10 mM in DMSO
  • AH 6809, EP1 and EP2 antagonist
  • 9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acid
  • Prostaglandin Receptor,AH-6809,inhibit,Inhibitor,AH6809,AH 6809
  • 9H-Xanthene-2-carboxylic acid, 6-(1-methylethoxy)-9-oxo-
  • AH6809;AH-6809
  • 6-Isopropoxy-9-oxo-9H-xanthene-2-carboxylic acid
  • 6-(1-Methylethoxy)-9-oxo-9H-xanthene-2-carboxylic acid
  • AH 6809
  • 6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID
  • 6-ISOPROPOXY-9-OXOXANTHENE-2-CARBOXYLIC ACID

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