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Testosterone phenylpropionate

CAS No.1255-49-8
Chemical Name:Testosterone phenylpropionate
CBNumber:CB6137357
Molecular Formula:C28H36O3
Formula Weight:420.58
MOL File:1255-49-8.mol

Testosterone phenylpropionate Property

Melting point 116.5 °C
Boiling point 497.74°C (rough estimate)
Density 1.0043 (rough estimate)
refractive index 1.5460 (estimate)
solubility DMF: 25 mg/mL; DMSO: 5 mg/mL; Ethanol: 15 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
Water Solubility 2.25mg/L(25 ºC)
InChIKey HHSXYDOROIURIP-FEZCWRLCSA-N
SMILES [C@@]12(CC[C@]3(C)[C@H](CC[C@@]3([H])[C@@]1(CCC1=CC(=O)CC[C@]21C)[H])OC(=O)CCC1C=CC=CC=1)[H] |&1:0,3,5,8,10,19,r|
CAS DataBase Reference 1255-49-8(CAS DataBase Reference)
FDA UNII 8GN84GWX51

Safety

Hazard Codes :Xn
Risk Statements :20/21/22-40
Safety Statements :22-36
WGK Germany :3
RTECS :XA3105000

NFPA 704:

	0
3		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H351-H361-H410
Precautionary statements P201-P273-P301+P312+P330-P308+P313

Testosterone phenylpropionate Chemical Properties,Usage,Production

Description Testosterone phenylpropionate (BAN; TPP) (brand name Testolent), or testosterone phenpropionate, also known as testosterone hydrocinnamate, is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester – specifically, the C17β phenylpropionate ester of testosterone – which was formerly marketed in Romania. It was first synthesized in 1951 and was first described in the literature by 1953. The medication was an ingredient of several isolated AAS commercial products, but was never widely used. Testosterone phenylpropionate was also notably a component of Sustanon and Omnadren, as well as of Estandron Prolongatum, Lynandron Prolongatum, and Mixogen. TPP was previously available in Great Britain.
Uses Testosterone 17-Phenylpropionate, is one of the 17b-fatty acid esters of testosterone, that is increasingly misused by athletes in an attempt to improve sports performance, and thus can be used in doping control. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.
Definition ChEBI: Testosterone phenylpropionate is a steroid ester.
Biological Functions Testosterone phenylpropionate is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester. It was first reported in the scientific literature in 1955 and was an ingredient of several isolated AAS commercial products, but was never widely used. Testosterone phenylpropionate was also notably a component of Sustanon and Omnadren.
Synthesis In a 100 ml reaction flask, 0.397 g (3 mmol) of cinnamaldehyde was added.0.411g (1.5mmol) Nandrolone, 0.06g (0.3mmol) [Bmim][OAc] catalyst, 10ml 1,4-dioxane, heated to 120 ?? C and then reacted for 2h, after the reaction was completed, cooled to room temperature, added 30 ml of water and 20 ml of ethyl acetate were extracted, and the phases were allowed to stand. The organic phase was concentrated and crystallized to obtain the target product. The yield was 64%.