Description
PAF C-
16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and ''
de novo'' pathways. It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-
6. Pathological processes involving PAF include necrotizing enterocolitis, inflammation, asthma, and allergy. PAF C-
16 Carboxylic acid is modified with a carboxylic acid group terminating the C-
16 alkyl chain. This provides a convenient site for chemical crosslinking.
