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2-Maleimido acetic acid

2-Maleimido acetic acid Structure
2-Maleimido acetic acid
  • CAS No.25021-08-3
  • Chemical Name:2-Maleimido acetic acid
  • CBNumber:CB61118111
  • Molecular Formula:C6H5NO4
  • Formula Weight:155.11
  • MOL File:25021-08-3.mol
2-Maleimido acetic acid Property
  • Melting point 114 °C(Solv: chloroform (67-66-3))
  • Boiling point 376.7±25.0 °C(Predicted)
  • Density 1.578±0.06 g/cm3(Predicted)
  • storage temp. under inert gas (nitrogen or Argon) at 2-8°C
  • solubility soluble in DMSO, Methanol
  • form powder to crystal
  • pka 3.31±0.10(Predicted)
  • color White to Almost white
  • InChI InChI=1S/C6H5NO4/c8-4-1-2-5(9)7(4)3-6(10)11/h1-2H,3H2,(H,10,11)
  • InChIKey GBKPNGVKZQBPCZ-UHFFFAOYSA-N
  • SMILES N1(CC(O)=O)C(=O)C=CC1=O
Safety
  • HS Code  :2925.19.4200
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302+H312+H332-H315-H319-H335
  • Precautionary statements P261-P280-P305+P351+P338
2-Maleimido acetic acid Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: M3143
  • Product name : 2-Maleimidoacetic Acid
  • Purity: 
  • Packaging: 50MG
  • Price: ₹2500
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: M3143
  • Product name : 2-Maleimidoacetic Acid
  • Purity: 
  • Packaging: 250MG
  • Price: ₹9500
  • Updated: 2022/05/26
  • Buy: Buy

2-Maleimido acetic acid Chemical Properties,Usage,Production

  • Chemical Properties White to Almost white powder to crystal or Pale Yellow Solid.
  • Uses Maleimidoacetic Acid (CAS# 25021-08-3) is a heterocyclic organic compound that has a variety of uses in organic synthesis. It contains both a maleimide and carboxylic acid functional group, making it a versatile reagent for coupling reactions with amine-containing compounds.
  • Application 2-Maleimido acetic acid is a maleimide-containing ligand that could be used to produce the cisplatin-based Pt(IV) complexes (OC-6-44)-diamminedichlorido(ethanolato)(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV) and (OC-6-44)-acetatodiamminedichlorido(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV). The Pt(IV) complexes are considered to act as antitumor prodrugs and their in vivo activity can be improved by exploiting drug targeting and delivery strategies[1]. In this case,  conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition.
  • References [1] Gabano E, et al. Conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition. Inorganica Chimica Acta, 2019; 488: 195-200.
2-Maleimido acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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2-Maleimido acetic acid Spectrum
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