ChemicalBook > CAS DataBase List > Indanidine
Indanidine
Indanidine
- CAS No.85392-79-6
- Chemical Name:Indanidine
- CBNumber:CB61117200
- Molecular Formula:C11H13N5
- Formula Weight:215.25
- MOL File:85392-79-6.mol
Indanidine Property
- Boiling point 413.3±37.0 °C(Predicted)
- Density 1.40±0.1 g/cm3(Predicted)
- storage temp. Store at -20°C
- solubility Soluble in DMSO
- pka 8.83±0.10(Predicted)
- form Solid
- color White to off-white
- FDA UNII MP564IFE34
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P305+P351+P338
Indanidine Chemical Properties,Usage,Production
- Uses Indanidine is an alpha-adrenergic agonist.
-
in vivo
The selective alpha 1-adrenoceptor agonist, Indanidine, also behaved as a partial agonist in the aorta and produced no significant contractions of the small mesenteric artery. Since Idazoxan and Indanidine have been reported to raise blood pressure in the pithed rat via an action at vascular alpha 1-adrenoceptors, these results call into question the reliability of the small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity in vivo[1].
- References [1] Van der Graaf PH, et al. Analysis of the action of idazoxan calls into question the reliability of the rat isolated small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity. Naunyn Schmiedebergs Arch Pharmacol. 1996 DOI:10.1007/BF00171074
Indanidine Preparation Products And Raw materials
Raw materials
Preparation Products
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85392-79-6, IndanidineRelated Search:
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- 化合物 T11651
- 吲达尼定
- 85392-79-6
- 2H-Indazol-4-amine, N-(4,5-dihydro-1H-imidazol-2-yl)-2-methyl-
- Unii-mp564ife34
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- Indanidine [inn]
- 4-(2-Imidazolin-2-ylamino)-2-methyl-2H-imidazole
- 2H-Imidazole, 4-(2-imidazolin-2-ylamino)-2-methyl-
- N-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-2H-indazol-4-amine
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- Indanidine