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SULFURETIN

SULFURETIN Structure
SULFURETIN
  • CAS No.120-05-8
  • Chemical Name:SULFURETIN
  • CBNumber:CB5774890
  • Molecular Formula:C15H10O5
  • Formula Weight:270.24
  • MOL File:120-05-8.mol
SULFURETIN Property
  • Melting point 295°C
  • storage temp. 2-8°C
  • form Solid
  • color Yellow to orange
  • LogP 1.980 (est)
  • FDA UNII M6410VY6MI
  • UNSPSC Code 12352200
  • NACRES NA.77
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
SULFURETIN Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: SML3002
  • Product name : Sulfuretin
  • Purity: ≥98% (HPLC)
  • Packaging: 5MG
  • Price: ₹14841.08
  • Updated: 2022/06/14
  • Buy: Buy

SULFURETIN Chemical Properties,Usage,Production

  • Uses Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].
  • Definition ChEBI: Sulfuretin is a member of 1-benzofurans.
  • Biological Activity Anti-adipogenic, antineoplastic activity, antioxidative stress, Anti-Inflammatory
  • in vivo

    Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation[1].

    Animal Model:Pathogen-free male BALB/c mice (7-8 weeks old)[1]
    Dosage:40 μg/kg
    Administration:A single intraperitoneal injection was administered 2 h after the last OVA challenge
    Result:Suppressed OVA-induced chemotaxis and airway inflammation.
  • References [1] Mi-Young Song, et al. Sulfuretin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2010 Sep 10;400(1):83-8. DOI:10.1016/j.bbrc.2010.08.014
    [2] Chen, H., et al. Isolation of sulfuretin and butin from Rhus verniciflua Stokes using medium-pressure liquid chromatography and their tyrosinase inhibitory effects. BioRes. 11(1), 759-771.
SULFURETIN Preparation Products And Raw materials
Raw materials
Preparation Products
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SULFURETIN Spectrum
120-05-8, SULFURETINRelated Search:
  • Aurones
  • 黄酮类
  • 抑制剂
  • 查尔酮
  • 中药对照品
  • 对照品
  • 植物提取物
  • (Z)-2-(3,4-二羟基苄亚基)-6-羟基苯并呋喃-3(2H)-酮
  • (Z)-2-(3,4-二羟基亚苄基)-6-羟基苯并呋喃-3(2H)-酮
  • 化合物SULFURETIN
  • 硫磺菊素
  • 2-(3,4-二羟基苯亚甲基)-6-羟基-3(2H)-苯并呋喃酮
  • 120-05-8
  • (Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one , Sulfuretin
  • (Z)-2-(3,4-Dihydroxybenzylidene)-6-hydroxybenzofuran-3(2H)-one
  • inflammation,platelet,Allergic,Sulfuretin,Nuclear factor-kappaB,Airway,Inhibitor,aggregation,monophenolase,diphenolase,NF-κB,mutagenesis,oxidative,Nuclear factor-κB,stress,Asthma,inhibit
  • 3(2H)-Benzofuranone, 2-[(3,4-dihydroxyphenyl)methylene]-6-hydroxy-, (2Z)-
  • 3',4',6-Trihydroxybenzalcoumaranone
  • 2-(3,4-Dihydroxybenzylidene)-6-hydroxy-3(2H)-benzofuranone
  • 2-[(Z)-(3,4-Dihydroxyphenyl)methylene]-6-hydroxybenzofuran-3(2H)-one
  • (Z)-2-[(3,4-Dihydroxyphenyl)methylene]-6-hydroxy-3(2H)-benzofuranone
  • SULFURETIN hplc
  • SULFURETIN WITH HPLC
  • SULPHURETIN
  • (Z)-2-[(3,4-dihydroxyphenyl)methylene]-6-hydroxy-2H-benzofuran-3-one
  • 2-(3,4-dihydroxybenzylidene)-6-hydroxy-2H-benzofuran-3-one
  • 3',4',6-TRIHYDROXYAURONE
  • 6,3',4'-TRIHYDROXYAURONE
  • SULFURETIN

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