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Chloroacetamide

CAS No.79-07-2
Chemical Name:Chloroacetamide
CBNumber:CB5691957
Molecular Formula:C2H4ClNO
Formula Weight:93.51
MOL File:79-07-2.mol

Chloroacetamide Property

Melting point 116-118 °C(lit.)
Boiling point 224.5 °C
Density 0.84
bulk density 760kg/m3
vapor pressure 0.05 mm Hg ( 20 °C)
refractive index 1.4480 (estimate)
Flash point 170 °C
storage temp. Store below +30°C.
solubility methanol: soluble1g/10 mL
form Crystalline Powder
pka 14.69±0.40(Predicted)
color White
PH 3.8-4.1 (40g/l, H2O, 20℃)
Water Solubility Soluble in water(90g/L).
Merck 14,2110
BRN 878191
InChIKey VXIVSQZSERGHQP-UHFFFAOYSA-N
LogP -0.530
CAS DataBase Reference 79-07-2(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances CHLORACETAMIDE
FDA 21 CFR 175.105; 176.170
EWG's Food Scores 5-8
FDA UNII 2R97846T1L
NIST Chemistry Reference Acetamide, 2-chloro-(79-07-2)
EPA Substance Registry System Acetamide, 2-chloro- (79-07-2)
UNSPSC Code 12352111
NACRES NA.22

Safety

Hazard Codes :T
Risk Statements :25-43-62
Safety Statements :22-36/37-45
RIDADR :UN 2811 6.1/PG 3
WGK Germany :2
RTECS :AB5075000
TSCA :Yes
HazardClass :6.1
PackingGroup :III
HS Code :29241900
Hazardous Substances Data :79-07-2(Hazardous Substances Data)
Toxicity :LD50 orally in Rabbit: 138 mg/kg LD50 dermal Rat > 2000 mg/kg

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H301-H317-H361f
Precautionary statements P201-P280-P301+P310+P330-P302+P352

Chloroacetamide Price More Price(13)

Brand: Sigma-Aldrich(India)
Product number: C0267
Product name : 2-Chloroacetamide
Purity: ≥98%
Packaging: 100G
Price: ₹2089.23
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: C0267
Product name : 2-Chloroacetamide
Purity: ≥98%
Packaging: 1KG
Price: ₹4005.25
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: C0267
Product name : 2-Chloroacetamide
Purity: ≥98%
Packaging: 500G
Price: ₹4384.13
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 8.02412
Product name : 2-Chloroacetamide
Purity: for synthesis
Packaging: 100G
Price: ₹3440
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 8.02412
Product name : 2-Chloroacetamide
Purity: for synthesis
Packaging: 1KG
Price: ₹9320
Updated: 2022/06/14
Buy: Buy

Chloroacetamide Chemical Properties,Usage,Production

Description Chloroacetamide is a preservative used in several applications such as in cutting metalwork fluids, in paints or in glues. It can induce contact dermatitis in hairdressers, or in shoemakers when used as a leather preservative.
Chemical Properties white crystalline powder
Uses preservative in cosmetic and pharmaceutical creams, shampoos, bath lotions, etc.; preservative in glues, cooling fluids.
Uses 2-Chloroacetamide is used as surface-active agent in home laundry, cleaning products & household formulated cleaners, other industrial uses, petroleum production, polymer processing.
Uses A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.
Flammability and Explosibility Non flammable
Contact allergens Chloroacetamide as a preservative is used in several applications as in cutting metalworking fluids, in paints or in glues. It can induce contact dermatitis in hairdressers or in shoemakers, being used as a leather preservative.
Safety Profile Poison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic Cland NOx. See also N-CHLOROACETAMIDE.
Synthesis Chloroacetamide can be prepared from chloroacetyl chloride and dry ammonia gas and by treating ethyl chloroacetate or methyl chloroacetate with cold aqueous ammonia solutions in a 2-l. A round-bottomed flask fitted with a mechanical stirrer and surrounded by an ice-salt bath is placed 215 g. (1.75 moles) of ethyl chloroacetate. Vigorous stirring is started, and 200 cc. of chilled aqueous ammonia (sp. gr. 0.9) is added to the cold ester. The solution is stirred in the cold for about fifteen minutes, then another 200. A portion of aqueous ammonia is added, and the stirring is continued for about fifteen minutes. The mixture is then allowed to stand for thirty minutes, filtered with suction, and washed with two 25-cc. portions of cold water to remove ammonium chloride. The yield of air-dried material melting at 118–119℃ is 128–138 g. This product contains traces of ammonium chloride, which may be removed by crystallization from water. When 100 g. of crude product is recrystallized from 400 cc. of water, about 80 g. of product Chloroacetamide is obtained. The recrystallized product melts at 119–120°.
Purification Methods Recrystallise the amide from acetone and dry it under vacuum over P2O5. [Beilstein 2 IV 490.]