Chemical Properties
white to light beige crystalline powder
Uses
3,5-dichloro-2-pyridoxyacetic acid derived from 3,5-dichloro-2-pyridone serves as a direct pyridine analog of the herbicide 2,4-dichlorophenoxyacetic acid[1]. 3,5-dichloro-2-pyridone is used as a reactant in the Mitsunobu reaction with ethyl lactate, diisopropyl azodicarboxylate, and triphenylphosphine in N,N-dimethylformamide at room temperature to produce both N-alkylated and O-alkylated products[2].
Definition
ChEBI: 3,5-Dichloro-1,2-dihydropyridin-2-one is a chloropyridine.
References
[1]
CAVA, M. P., BHATTACHARYYA, N. K. (1958). Pyridine Derivatives. II. Some Halogen Substituted 2-Pyridoxyacetic Acids
1. The Journal of Organic Chemistry, 23(11), 1614–1616.
https://doi.org/10.1021/jo01105a007[2]
Torhan, M. C., Peet, N. P., Williams, J. D. (2013). A comparison of N- versus O-alkylation of substituted 2-pyridones under Mitsunobu conditions. Tetrahedron Letters, 54(30), 3926–3928.
https://doi.org/10.1016/j.tetlet.2013.05.054
