ChemicalBook > CAS DataBase List > ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE
ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE
- CAS No.71774-13-5
- Chemical Name:ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE
- CBNumber:CB5506390
- Molecular Formula:C10H12N5O5PS
- Formula Weight:345.27
- MOL File:71774-13-5.mol
ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Property
- Boiling point 648.0±65.0 °C(predicted)
- Density 2.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
- storage temp. Desiccate at -20°C
- pka -0.55±0.60(predicted)
- form crystalline solid
- Water Solubility water: 20mg/mL
- UNSPSC Code 12352200
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Chemical Properties,Usage,Production
- Uses (S)-Adenosine, cyclic 3'',5''-(hydrogenphosphorothioate) triethylammonium is an activator of PKA.
- Definition ChEBI: (Sp)-cAMPS is a nucleoside 3',5'-cyclic phosphorothioate having adenine as the nucleobase (the Sp-stereoisomer). It has a role as a protein kinase agonist. It is a member of purines and a nucleoside 3',5'-cyclic phosphorothioate. It is functionally related to a 3',5'-cyclic AMP.
- Biological Activity Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor.
-
in vivo
In chronic alcohol consumption (CAC) mice, direct infusion of the Sp-cAMPS (1 μg/μL) into the prefrontal cortex significantly improves or impairs, respectively, working memory performance in withdrawn and water animals[5].
- IC 50 PKA I; PKA II; PDE3A: 47.6 μM (Ki); PDE10 GAF domain: 50 μM (EC50)
ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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71774-13-5, ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATERelated Search:
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- Cyclic Nucleotide related
- 抑制剂
- C10H12N5O5PSC6H16N
- (S)-腺苷环3',5'-(硫代磷酸氢根)三乙铵
- 化合物 SP-CAMPS
- 化合物 T28615
- 71774-13-5
- Sp cAMPS,SpcAMPS
- Rp-cAMPS TEA salt
- Rp cAMPS TEA salt
- Adenosine, cyclic 3',5'-[hydrogen (S)-phosphorothioate]
- Adenosine-3'',5''-cyclic monophosphothioate sodium salt Sp isomer
- ADENOSINE3,5-CYCLICMONOPHOSPHOTHIOATESP-ISOMERTRIETHYLAMMONIUMSALT,HIGHPURITY
- (S)-ADENOSINE, CYCLIC 3',5'-(HYDROGENPHOSPHOROTHIOATE) TRIETHYLAMMONIUM
- Triethylammoniumsalt
- cAMPS-Sp
- (S)-Adenosine
- ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE
- camps,sp-isomer,teasalt
- adenosine-3’,5’-cyclicmonophosphorothioate,sp-isomer(sp-camps),sodiumsalt
