Description
ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria. It is used by amylose synthases or starch synthases in plastids in the production of amylose, amylopectins, starch, and other polysaccharides. ADPG is normally generated within plastids, although it can be biosynthesized in the cytoplasm of certain grasses and imported into plastids by a membrane-bound transporter.
Uses
glucose transferase substrate
Uses
Adenosine-5′-diphosphoglucose disodium salt has been used as a component of the reaction mixture to measure the enzymatic activity of adenosine-5′-diphosphate (ADP)-glucose pyrophosphorylase (AGPase) and for the synthesis of starch.
Biochem/physiol Actions
Adenosine-5′-diphosphoglucose (ADP-Glucose) is a substrate widely used as a glucose donor. It is a substrate starch synthase (EC 2.4.1.21) in starch synthesis. ADP-glucose is a substrate for α-1,4-glucan-protein synthase (ADP-forming) (EC 2.4.1.113), ADP-glucose pyrophosphorylases and many glucosyltransferases.
References
[1] STEVEN G BALL Matthew K M. From bacterial glycogen to starch: understanding the biogenesis of the plant starch granule.[J]. Annual review of plant biology, 2003, 54: 207-233. DOI:
10.1146/annurev.arplant.54.031902.134927[2] TOUNKANG SAMBOU. Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice.[J]. Molecular Microbiology, 2008, 70 3: 762-774. DOI:
10.1111/j.1365-2958.2008.06445.x[3] SYLVIANE COMPAROT-MOSS K D. The evolution of the starch biosynthetic pathway in cereals and other grasses.[J]. Journal of Experimental Botany, 2009, 60 9: 2481-2492. DOI:
10.1093/jxb/erp141
