ChemicalBook > CAS DataBase List > Boc-D-Ser(Bzl)-OH
Boc-D-Ser(Bzl)-OH
Boc-D-Ser(Bzl)-OH
- CAS No.47173-80-8
- Chemical Name:Boc-D-Ser(Bzl)-OH
- CBNumber:CB5438415
- Molecular Formula:C15H21NO5
- Formula Weight:295.33
- MOL File:47173-80-8.mol
Boc-D-Ser(Bzl)-OH Property
- Melting point 58-60 °C(lit.)
- alpha -19 º (c=2 80% alcohol)
- Boiling point 437.02°C (rough estimate)
- Density 1.1454 (rough estimate)
- refractive index -20 ° (C=2, 80% EtOH)
- storage temp. Sealed in dry,Room Temperature
- solubility almost transparency in Methanol
- pka 3.53±0.10(Predicted)
- form Powder
- color White
- BRN 2665080
- InChI InChI=1S/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)10-20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1
- InChIKey DMBKPDOAQVGTST-GFCCVEGCSA-N
- SMILES C(O)(=O)[C@@H](COCC1=CC=CC=C1)NC(OC(C)(C)C)=O
- CAS DataBase Reference 47173-80-8(CAS DataBase Reference)
- UNSPSC Code 12352209
- NACRES NA.22
Safety
- Hazard Codes :Xn
- Risk Statements :20/21/22-36/37/38
- Safety Statements :24/25-36-26
- WGK Germany :3
- HS Code :2924 29 70
- HazardClass :IRRITANT
-
NFPA 704:
1 0 0
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319-H335
- Precautionary statements P261-P305+P351+P338
Boc-D-Ser(Bzl)-OH Price
More Price(4)
- Brand: Sigma-Aldrich(India)
- Product number: 8.53111
- Product name : Boc-D-Ser(Bzl)-OH
- Purity: Novabiochem?
- Packaging: 25G
- Price: ₹13090
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: 15078
- Product name : Boc-D-Ser(Bzl)-OH
- Purity: ≥98.0% (HPLC)
- Packaging: 5G
- Price: ₹20491.73
- Updated: 2022/06/14
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: B1863
- Product name : O-Benzyl-N-(tert-butoxycarbonyl)-D-serine
- Purity:
- Packaging: 1G
- Price: ₹3800
- Updated: 2022/05/26
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: B1863
- Product name : O-Benzyl-N-(tert-butoxycarbonyl)-D-serine
- Purity:
- Packaging: 5G
- Price: ₹16200
- Updated: 2022/05/26
- Buy: Buy
Boc-D-Ser(Bzl)-OH Chemical Properties,Usage,Production
- Chemical Properties White crystalline powder
- Uses N-BOC-O-Benzyl-D-serine, is an amino acid derivative used in chemical synthesis and peptide chemistry.is used in preparation of substituted naphthyl thiadiazolidinones as protein tyrosine phosphatase degraders for treating cancer and metabolic diseases.
- reaction suitability reaction type: Boc solid-phase peptide synthesis
- Biological Activity Boc-O-benzyl-D-serine is an inhibitor of the uptake of galactose and its derivatives. It has potent inhibitory activity against the uptake of galactose, glucose, and lactose. This drug is also effective in inhibiting the uptake of tetrazole, a substance that inhibits glycolysis. Boc-O-benzyl-D-serine is able to inhibit atherosclerotic lesions caused by piperidine, which has been shown to be synthesized from benzyl alcohol and piperidine. The oral administration of this compound can enhance fibroblast cells that are resistant to insulin.
- Synthesis N-Boc D-Se (500 mg, 2.43 mmol) dissolved in anhydrous DMF (4 mL) was slowly added to a dispersion of 60% NaH (204 mg, 5.1 mmol) in anhydrous DMF at 0 ° C. Stir the mixture at room temperature for 1 hour and cool to 0 ° C. Subsequently, benzyl bromide (0.29 mL, 2.43 mmol) was added and the mixture was heated to room temperature. After 4 hours of reaction, add saturated NH4Cl (1 mL) to quench the reaction. Finally, the product Boc-D-Ser(Bzl)-OH was obtained through purification.
Boc-D-Ser(Bzl)-OH Preparation Products And Raw materials
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47173-80-8, Boc-D-Ser(Bzl)-OHRelated Search:
- Benzyl chloride D-Serine Benzyl benzoate L-Homoserine tert-Butanol Boc-Ser(tBu)-OH N-Carbobenzyloxyglycine Benzyl bromide DL-Serine Benzyltriethylammonium chloride Benzyl alcohol L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE Boc-Aib-OH D-Cycloserine Benzyltrimethylammonium chloride Boc-O-benzyl-L-serine, N-(tert-Butoxycarbonyl)-O-benzyl-L-serine,N-BOC-O-Benzyl-L-serine,N-T-BOC-O-BENZYL-L-SERINE CRYSTALLINE BOC-GLY-LEU-OH Boc-His(Trt)-OH
- Boc-Amino acid series
- Boc-Amino Acids
- Biochemistry
- Amino Acids (N-Protected)
- Boc-Amino Acids and Derivative
- Amino Acids
- 黄金产品
- 抑制剂
- 生化试剂
- 化学试剂
- 产品
- 对照品
- 药物杂质及中间体
- 合成
- 胺基酸
- 非天然氨基酸
- 保护氨基酸
- 医药中间体
- 氨基酸
- Boc-保护氨基酸
- Amino Acids (N-Protected)
- Protected & Labeled Amino Acids
- Boc-Amino Acids
- Amino Acid Derivatives
- Serine
- Peptide Synthesis
- Specialty Synthesis
- C15H20NO5
- 47173-80-6
- 47473-80-8
- 化合物 BOC-D-SER(BZL)-OH
- N-BOC-O-苄基-D-丝氨酸,≥98.0%(HPLC)
- N-叔丁氧羰基-O-苄基-DL-丝氨酸
- O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE O-苄基-N-(叔丁氧羰基)-D-丝氨酸
- O-苄基-N-BOC-D-丝氨酸
- N-BOC-O-苯基-D-丝氨酸
- N-叔丁氧羰基-O-苄基-D-丝氨酸
- N-Boc-O-苄基-D-丝氨酸
- N-BOC-O-苄基-D-丝氨酸,99%
- O-苄基-N-(叔丁氧羰基)-D-丝氨酸
- N -叔丁- O -苄基- D -丝氨酸
- N-叔丁氧羰基-O苄-D-丝氨酸
- BOC-O-苄基-D-丝氨酸
- 叔丁氧羰基-D-丝氨酸Β苄醚
- (R)-3-(苄氧基)-2-((叔-丁氧羰基)氨基)丙酸
- (2R)-2-(三级丁氧基羰基氨基)-3-(苯基甲氧基)丙酸
- (2R)-2-[(2-甲基丙-2-基)氧基羰基氨基]-3-(苯基甲氧基)丙酸
- (2R)-2-[(三级丁氧基-氧代甲基)氨基]-3-(苯基甲氧基)丙酸
- (2S)-2-[(2-甲基丙-2-基)氧基羰基氨基]-3-(苯基甲氧基)丙酸
- N-BOC-O-苄基-D-丝氨酸 BOC-D-SER(BZL)-OH
- 47173-80-8
- Boc-<sc>D</sc>-Ser(Bzl)-OH
- BOC-D-Ser(OBZL)-OH
- (s)-(+)-3-Benzyloxy-2-(Boc-amino)-1-propanol
- N-[(1,1-Dimethylethoxy)carbonyl]-O-(phenylmethyl)-D-serine
- (2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid
- BOC-D-SER(BZL)
- O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE