2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline

Chemical Properties

Beige Powder

Uses

IQ is highly mutagenic in the Ames test. Investigations have shown that this compound may be present in broiled fish, fried beef, commercial beef extracts and protein pyrolysates

Definition

ChEBI: An imidazoquinoline that is 3H-imidazo[4,5-f]quinoline substituted by a methyl group at position 3 and an amino group at position 2.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 30, p. 1857, 1982 DOI: 10.1248/cpb.30.1857
Synthetic Communications, 18, p. 973, 1988 DOI: 10.1080/00397918808060881

General Description

Light tan crystalline solid or tan powder.

Air & Water Reactions

2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is sensitive to light and air. Insoluble in water.

Reactivity Profile

2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE may be sensitive to prolonged exposure to heat. 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is stable under moderately acidic and alkaline conditions and in cold dilute aqueous solutions when protected from light. 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is rapidly degraded by dilute hypochlorite.

Health Hazard

ACUTE/CHRONIC HAZARDS: It may emit potentially toxic fumes when involved in a fire.

Fire Hazard

Flash point data for 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE are not available; however, 2-AMINO-3-METHYL-3H-IMIDAZO[4,5-F]QUINOLINE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,

Carcinogenicity

IQ is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.