QUININE SULFATE
- CAS No.549-56-4
- Chemical Name:QUININE SULFATE
- CBNumber:CB5323302
- Molecular Formula:C40H50N4O8S
- Formula Weight:746.91
- MOL File:549-56-4.mol
- Boiling point 695℃[at 101 325 Pa]
- vapor pressure 0Pa at 25℃
- FEMA 2975 | QUININE BISULFATE
- form Solid
- color White to off-white
- Odor odorless
- Water Solubility 10.8g/L at 25℃
- BCS Class 1
- LogP -2.22 at 25℃
- CAS DataBase Reference 549-56-4(CAS DataBase Reference)
- Substances Added to Food (formerly EAFUS) QUININE BISULFATE
- FDA UNII M201HC068W
- EPA Substance Registry System Quinine sulfate (1:1) (549-56-4)
- RIDADR :1544
- HazardClass :6.1(b)
- PackingGroup :III
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H317
- Precautionary statements P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501
QUININE SULFATE Chemical Properties,Usage,Production
-
Chemical Properties
Basic quinine sulfate is C40H50N4O8S; the dilIyrate, C40H50N4O8S·2H20, is dull needles or rods making a light and readily compressible mass that becomes brownish on exposure to light. Slightly soluble in chloroform and ether. Should be kept well closed and protected from light.
Uses are as a protective colloid in preparation of metallic colloidal solutions, photography, dyes, intermediates, synthetic drugs, medicine (antibacterial), process engraving, laboratory reagent, gas analysis (an oxygen absorber), reducing agent, and antioxidant in lubricating oils. - Chemical Properties Quinine bisulfate has no odor, but has a bitter taste.
- Physical properties Crystals or crystalline powder. White when fresh, but may acquire a brownish tint upon exposure to air.
- Uses Antiprotozoal (malaria).
- Uses Quinine Bisulfate (cas# 549-56-4) is a compound useful in organic synthesis.
- Flammability and Explosibility Non flammable
-
in vivo
Quinidine sulfate is rapidly absorbed, with peak plasma concentrations 60-90 min after an oral dose. Other salts (gluconate, polygalacturonate) are more slowly absorbed, with lower peak concentrations[2].
Quinidine sulfate is approximately 70-90 % bound to plasma proteins. It undergoes hepatic oxidative metabolism to form an N-oxide, a 3-hydroxy form, an O-demethyl form and 2'-quinidinone[2].
Quinidine sulfate inhibits metabolism of amphetamine in rats. Quinidine sulfate pretreatment results in a significant decrease in the excretion of p-hydroxyamphetamine at 24 and 48 h to 7.2 and 24.1% of the vehicle-control levels, respectively, accompanied by a significant increase in amphetamine excretion between 24 and 48 h to 542% of the control[3]. - IC 50 Plasmodium
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- QUINUCLIDINE Quinine Quinine sulfate dihudrate Quinine, sulfate (2:1) (salt) (8CI),QUININE SULFATE Quinine sulfate *Fluorescence Reference Standard QUININE SULFATE USP(CRM STANDARD) QUININE SULFATE, FLUORESCENCE QUININE SULFATE SALT quinine,sulfate(1:1)(salt),heptahydrat QUININE SULFATE Quinine sulfate dihydrate QUININE SULFATE Quinine hydrochloride dihydrate QUININE SULFATE SALT MONOHYDRATE
- 抑制剂
- C20H24N2O2H2SO4
- 奎宁杂质10(硫酸氢盐)
- 硫酸金雞鈉鹼
- 奎宁重硫酸盐
- 549-56-4
- Cyproconazole Impurity 4
- Quinine Impurity 10(Bisulfate)
- (R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol sulfate
- (5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl)-(6-methoxyquinolin-4-yl)methanol
- Quinine BisulphateQ: What is Quinine Bisulphate Q: What is the CAS Number of Quinine Bisulphate Q: What is the storage condition of Quinine Bisulphate
- (1R)-(6-Methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)Methanol sulfate
- Sulfuric acid quinine
- Cinchonan-9-ol, 6-methoxy-, (8.alpha.,9R)-, sulfate (1:1) (salt)
- quinine hydrogen sulphate
- Quinine Bisulphate
- QUININE SULFATE
- QUININE HEMISULFATE
- 6-METHOXYCINCHONINE SULFATE
- A-(6-METHOXY-4-QUINOLYL)-5-VINYL-2-QUINUCLIDINE-METHANOL SULFATE
- 6’-methoxy-cinchonan-9-o(8alpha,9theta)-cinchonan-9-osulfate(1:1)(salt)
- QUININE BISULFATE
- Quinine sulfate (1:1) (salt)