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CONDURITOL B EPOXIDE

CAS No.6090-95-5
Chemical Name:CONDURITOL B EPOXIDE
CBNumber:CB5316315
Molecular Formula:C6H10O5
Formula Weight:162.14
MOL File:6090-95-5.mol

CONDURITOL B EPOXIDE Property

Melting point 157-159
Boiling point 360.5±42.0 °C(Predicted)
Density 1.925±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C
solubility Soluble in Water (up to 25 mg/ml) or in DMSO
form White solid
pka 13.08±0.70(Predicted)
color White
biological source synthetic (organic)
Water Solubility water: 20mg/mL, clear, colorless to faintly yellow
Stability Moisture Sensitive
NCI Dictionary of Cancer Terms CBE
FDA UNII NHM754Q310
UNSPSC Code 12352119
NACRES NA.77

Safety

WGK Germany :3
Hazard Note :Harmful
HS Code :2932990090

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P271-P280

CONDURITOL B EPOXIDE Price More Price(3)

Brand: Sigma-Aldrich(India)
Product number: C5424
Product name : Conduritol B epoxide
Purity:
Packaging: 5MG
Price: ₹14797.78
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: C5424
Product name : Conduritol B epoxide
Purity:
Packaging: 25MG
Price: ₹52771.88
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 234599
Product name : Conduritol B Epoxide - CAS 6090-95-5 - Calbiochem
Purity: Conduritol B Epoxide, CAS 6090-95-5, is an irreversible Inhibitor of glucocerebrosidase in neurons. Also inhibits α-glucosidase activity in a variety
Packaging: 100MG
Price: ₹33440
Updated: 2022/06/14
Buy: Buy

CONDURITOL B EPOXIDE Chemical Properties,Usage,Production

Description Conduritol B epoxide (6090-95-5) is a β-Glycosidase inhibitor.1,2 May be used for generation of the “Gaucher mouse”3 and the in vitro model of the Gaucher cell4.
Chemical Properties White Crystalline Solid
Uses inhibitor of glucosidases
Definition ChEBI: 1-D-1,2-anhydro-myo-inositol is a conduritol epoxide resulting from the formal epoxidation of the double bond of (+)-conduritol B. It has a role as an EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor and an EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor. It is functionally related to a (+)-conduritol B. It is an enantiomer of a 1-L-1,2-anhydro-myo-inositol.
General Description Conduritol B epoxide?(CBE) is a mix of 1-L-1,2-anhydro-myo-inositol and 1-D-1,2-anhydro-myo-inositol.
Biochem/physiol Actions Conduritol B epoxide?(CBE)?is capable of inactivating sucrase-isomaltase irreversibly. It can be used to produce cell and animal models to study on Gaucher disease (GD) and Parkinson′s disease (PD).
storage Store at -20°C
References 1) Datta and Radin (1988), Normalization of liver glucosylceramide levels in the “Gaucher” mouse by phosphatidylserine injection;? Biochem. Biophys. Res. Commun., 152 155 2) Radin and Vunnam (1981), Inhibitors of cerebroside metabolism;? Methods Enzymol., 72 673 3) Stephens et al. (1981), Distribution of conduritol B epoxide in the animal model for gaucher’s disease (Gaucher mouse); Biochim. Biophys. Acta, 672 29 4) Newburg et al. (1986), beta-Glucosidase inhibition in murine peritoneal macrophages by conduritol-B-epoxide: an in vitro model of the Gaucher cell;? Biochim. Biophys. Acta, 877 121