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Diproteverine

Diproteverine Structure
Diproteverine
  • CAS No.69373-95-1
  • Chemical Name:Diproteverine
  • CBNumber:CB51116554
  • Molecular Formula:C26H35NO4
  • Formula Weight:425.565
  • MOL File:69373-95-1.mol
Diproteverine Property
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Diproteverine Chemical Properties,Usage,Production

  • Uses Diproteverine (BRL 40015) is an oral activity calcium channel blocker. Diproteverine embryonic toxicity. Diproteverine also shows antianginal properties[1][2].
  • in vivo

    Diproteverine (40, 80, 160, 320 mg/kg; p.o.; daily for 10 days) shows embryonic toxicity in rats[1].

    Animal Model:Sprague-Dawley virgin female rats[1]
    Dosage:40, 80, 160, 320 mg/kg
    Administration:P.o.; daily for 10 days
    Result:Induced embryonic deaths, significantly increased incidence of fetuses showing an unusual pattern of digital, tail, heart, and vertebral abnormalities.
  • References [1] Ridings JE, et al. Prenatal toxicity studies in rats and rabbits with the calcium channel blocker diproteverine. Reprod Toxicol. 1996 Jan-Feb;10(1):43-9. DOI:10.1016/0890-6238(95)02017-9
    [2] Lacroix P, et al. Diproteverine (BRL 40015): a new type of calcium antagonist with potential antianginal properties. Eur J Pharmacol. 1991 Jan 17;192(3):317-27. DOI:10.1016/0014-2999(91)90220-k
Diproteverine Preparation Products And Raw materials
Raw materials
Preparation Products
Diproteverine Suppliers
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Diproteverine Spectrum
69373-95-1, DiproteverineRelated Search:
  • 抑制剂
  • C26H35NO4
  • 化合物 DIPROTEVERINE
  • 化合物 T27183
  • 二丙维林
  • 69373-95-1
  • 1-[(3,4-diethoxyphenyl)methyl]-6,7-di(propan-2-yloxy)-3,4-dihydroisoquinoline
  • BRL-40015
  • 1-[(3,4-Diethoxyphenyl)methyl]-3,4-dihydro-6,7-bis(1-methylethoxy)isoquinoline
  • Diproteverine

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