ChemicalBook > CAS DataBase List > 6-BROMO-2,4-DICHLOROQUINAZOLINE

6-BROMO-2,4-DICHLOROQUINAZOLINE

6-BROMO-2,4-DICHLOROQUINAZOLINE Structure
6-BROMO-2,4-DICHLOROQUINAZOLINE
  • CAS No.102393-82-8
  • Chemical Name:6-BROMO-2,4-DICHLOROQUINAZOLINE
  • CBNumber:CB51012890
  • Molecular Formula:C8H3BrCl2N2
  • Formula Weight:277.93
  • MOL File:102393-82-8.mol
6-BROMO-2,4-DICHLOROQUINAZOLINE Property
  • Boiling point 330.2±24.0 °C(Predicted)
  • Density 1.851±0.06 g/cm3(Predicted)
  • storage temp. Inert atmosphere,Store in freezer, under -20°C
  • pka -1.19±0.30(Predicted)
  • form Solid
  • color Off-white
  • Water Solubility Slightly soluble in water.
  • InChI InChI=1S/C8H3BrCl2N2/c9-4-1-2-6-5(3-4)7(10)13-8(11)12-6/h1-3H
  • InChIKey LBAYOWRVZAKPLS-UHFFFAOYSA-N
  • SMILES N1=C2C(C=C(Br)C=C2)=C(Cl)N=C1Cl
Safety
  • HS Code  :2933599590
  • NFPA 704:
    1
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a

6-BROMO-2,4-DICHLOROQUINAZOLINE Chemical Properties,Usage,Production

  • Uses It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.
  • Synthesis The synthesis of 6-BROMO-2,4-DICHLOROQUINAZOLINE is as follows:BTC (0.65 g, 2.2 mmol in 6mL of PhCl) was added to astirred solution of tris(4-methoxyphenyl)phosphine oxide 3d(0.33 g, 0.9 mmol in 5mL PhCl) dropwise in a round botttomflask placed on an ice bath. After complete addition,the mixture was stirred for 30 min at room temperature.Then isatin-3-oximes (3 mmol) were added, and the mixturewas heated to 120 C until completion of the reaction(followed by TLC, n-hexane/ethyl acetate 10:1). Aftercooling, the mixture was then poured into 50mL ice waterand extracted with ethyl acetate (320 mL). The organiclayer was dried over anhydrous Na2SO4 and concentrated invacuo. The crude product was purified over column chromatography(n-hexane/ethyl acetate 10:1) to afford thepure produce 2,4-dichloroquinazolins. Tris(4-methoxyphenyl)phosphine oxide 3d was recovered by column chromatography(n-hexane/ethyl acetate 1:1).
    synthesis of 6-BROMO-2,4-DICHLOROQUINAZOLINE
6-BROMO-2,4-DICHLOROQUINAZOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
6-BROMO-2,4-DICHLOROQUINAZOLINE Suppliers
Global(159)Suppliers
  • Supplier：
    Capot Chemical Co.,Ltd.
  • Tel：+86-（0）57185586718<br/>+86-13336195806
  • Email：sales@capot.com
  • Country：China
  • ProdList：29730
  • Advantage：60
  • Supplier：
    Alchem Pharmtech,Inc.
  • Tel：8485655694
  • Email：sales@alchempharmtech.com
  • Country：United States
  • ProdList：63687
  • Advantage：58
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
  • Supplier：
    Richest Group Ltd
  • Tel：18017061086
  • Email：oled@richest-group.com
  • Country：CHINA
  • ProdList：5600
  • Advantage：58
  • Supplier：
    Win-Win chemical CO., Limited
  • Tel：+86-0086-577-64498589<br/>+86-15355981851
  • Email：sales@win-winchemical.com
  • Country：China
  • ProdList：14442
  • Advantage：58
6-BROMO-2,4-DICHLOROQUINAZOLINE Spectrum
102393-82-8, 6-BROMO-2,4-DICHLOROQUINAZOLINERelated Search:
  • CHIRAL CHEMICALS
  • 高端化学
  • 订做
  • 苯并嘧啶
  • 医药中间体
  • C8H3BrCl2N2
  • 2,4-二氯-6-溴喹唑啉
  • 6-溴-2,4-二氯喹唑啉
  • 102393-82-8
  • 6-Bromo-2,4-dichloroquinazoline,97%
  • Quinazoline, 6-bromo-2,4-dichloro-
  • 6-broMo-2,4-dichlroquinazoline
  • 4-dichloroquinazoline
  • 2,4-Dichloro-6-broMoquinazoline
  • 6-Bromo-2,4-dichloroquina...
  • 6-BROMO-2,4-DICHLOROQUINAZOLINE

Home

My