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2,4-DICHLOROQUINOLINE

2,4-DICHLOROQUINOLINE Structure
2,4-DICHLOROQUINOLINE
  • CAS No.703-61-7
  • Chemical Name:2,4-DICHLOROQUINOLINE
  • CBNumber:CB4757939
  • Molecular Formula:C9H5Cl2N
  • Formula Weight:198.05
  • MOL File:703-61-7.mol
2,4-DICHLOROQUINOLINE Property
  • Melting point 52-54
  • Boiling point 282°C(lit.)
  • Density 1.4178 (rough estimate)
  • refractive index 1.6610 (estimate)
  • storage temp. Keep in dark place,Sealed in dry,Room Temperature
  • solubility Chloroform, Methanol
  • pka -1.10±0.50(Predicted)
  • form Solid
  • color White
  • λmax 305nm(MeOH)(lit.)
  • InChIKey QNBJYUUUYZVIJP-UHFFFAOYSA-N
  • CAS DataBase Reference 703-61-7(CAS DataBase Reference)
Safety
  • Hazard Codes  :Xi,T
  • Risk Statements  :36/37/38-41-37/38-25
  • Safety Statements  :26-36-45-39
  • RIDADR  :2811
  • WGK Germany  :3
  • Hazard Note  :Irritant
  • HazardClass  :6.1
  • PackingGroup  :Ⅲ
  • HS Code  :2933491090
  • NFPA 704:
    0
    1 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301-H315-H318-H335-H319
  • Precautionary statements P261-P280-P301+P310-P305+P351+P338-P264-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
2,4-DICHLOROQUINOLINE Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: D4452
  • Product name : 2,4-Dichloroquinoline
  • Purity: min. 98.0 %
  • Packaging: 5G
  • Price: ₹8500
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: D4452
  • Product name : 2,4-Dichloroquinoline
  • Purity: min. 98.0 %
  • Packaging: 25G
  • Price: ₹21800
  • Updated: 2022/05/26
  • Buy: Buy

2,4-DICHLOROQUINOLINE Chemical Properties,Usage,Production

  • Uses 2,4-Dichloroquinoline is used in the synthesis of tRNA synthetase inhibitors with antibacterial activity against gram-positive bacteria. Also used in the preparation of arylquinolines displaying anthelmintic properties.
  • Synthesis The synthesis of 2,4-dichloroquinoline is as follows:A suspension of quinoline-2,4-diol (150 g, 931 mmol) in POCl3 (975 mL, 10.4 mol) was stirred at reflux for 6 hr and the reaction mixture was concentrated. The residue was diluted with CHCl3 (500 mL) and the solution was poured into ice water. The aqueous layer was extracted with CHCl3 (three times). The combined organic layer was dried over MgSO4, filtrated, concentrated, and purified by flash chromatography (silica gel, 20% EtOAc in hexane) to give 2,4-dichloroquinoline (177 g, 96%) as a pale brown solid.  
    synthesis of 2,4-DICHLOROQUINOLINE
2,4-DICHLOROQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-DICHLOROQUINOLINE Suppliers
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2,4-DICHLOROQUINOLINE Spectrum
703-61-7, 2,4-DICHLOROQUINOLINERelated Search:
  • pharmacetical
  • 高端化学
  • 医药化工类
  • 有机化学
  • 合成
  • C9H5CI2N
  • 2,4-二氯喹啉
  • 703-61-7
  • 2,4-Dichloroquinoline&gt
  • Quinoline,2,4-dichloro-
  • 2-4-Dichloro-1-azanaphthalene
  • 2,4-dichloroquinoline(SALTDATA: FREE)
  • 2,4-Dichloroquinoline 98%
  • IFLAB-BB F1706-0118
  • AURORA KA-3862
  • 2,4-DICHLOROQUINOLINE

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