Chemical Properties
colorlesstolightyellowliqui
Uses
3-Bromo-4-chlorobenzotrifluoride serves as a starting material for synthesizing 2,2,6-tris(trifluoromethyl)-2H-chromene via palladium-catalyzed coupling with trimethylsilylacetylene followed by further reactions[1].
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 1651, 1950
DOI: 10.1021/ja01160a063
References
[1]Sosnovskikh, V. Y., Usachev, B. I., Sevenard, D. V., & Röschenthaler, G.-V. (2005). Nucleophilic trifluoromethylation of RF-containing 4-quinolones, 8-aza- and 1-thiochromones with (trifluoromethyl)trimethylsilane. Journal of Fluorine Chemistry, 126(5), 779–784.
https://doi.org/10.1016/j.jfluchem.2005.03.001
