Uses
Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-β-N-acetylglucosaminidase (Endo A) can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-β-N-acetylglucosaminidase (Endo A) catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline[1].
General Description
Endoglycosidase H or endo-β-
N-acetylglucosaminidase His an glycohydrolase. It is produced by
Streptomyces plicatus and other
Streptomyces species.
Biochem/physiol Actions
Endoglycosidase H is involved in cleaving the N-linked glycans present between the twoN-acetylglucosamine (GlcNAc) residues in the core of the glycan chain in high-mannose sugars.
References
[1] Yin J, et al. Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A. PLoS One. 2009;4(3):e4658. DOI:
10.1371/journal.pone.0004658
