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IGF-I (24-41)

IGF-I (24-41) Structure
IGF-I (24-41)
  • CAS No.135861-49-3
  • Chemical Name:IGF-I (24-41)
  • CBNumber:CB4493158
  • Molecular Formula:C88H133N27O28
  • Formula Weight:2017.16
  • MOL File:135861-49-3.mol
IGF-I (24-41) Property
  • Density 1.56±0.1 g/cm3(Predicted)
  • storage temp. -15°C
  • form Solid
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

IGF-I (24-41) Chemical Properties,Usage,Production

  • Uses IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development[1][2][3].
  • in vivo

    IGF-I (24-41) (ICV; 200 ng dose; 2 μL; postnatal days 2, 4, and 7) regulates somatic growth and behavioral development[2].

    Animal Model:Mice of an outbred Swiss-derived strain (CD-l) weighing 30-33g (virgin males) or 28-30g (nulliparous females)[2]
    Dosage:200 ng dose; 2 μL
    Administration:ICV; postnatal days (PND) 2, 4, and 7
    Result:Increased the rate of ultrasonic calls of the pups measured on PND8.
  • References [1] Puche JE, et al. Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med. 2012 Nov 14;10:224. DOI:10.1186/1479-5876-10-224
    [2] D Santucci, et al. IGF-I and IGF-I24-41 but not IGF-I57-70 affect somatic and neurobehavioral development of newborn male mice. Brain Res Bull. 1994;35(4):367-71. DOI:10.1016/0361-9230(94)90115-5
    [3] Dan Meng, et al. Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species. Free Radic Biol Med. 2007 Jun 1;42(11):1651-60. DOI:10.1016/j.freeradbiomed.2007.01.037
IGF-I (24-41) Preparation Products And Raw materials
Raw materials
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IGF-I (24-41) Spectrum
135861-49-3, IGF-I (24-41)Related Search:
  • 多肽
  • 标准品
  • C88H133N27O28
  • IGF-I 24-41;INSULIN-LIKE GROWTH FACTOR I (24-41)
  • 135861-49-3
  • YFNKPTGYGSSSRRAPQT
  • L-Threonine, L-tyrosyl-L-phenylalanyl-L-asparaginyl-L-lysyl-L-prolyl-L-threonylglycyl-L-tyrosylglycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-
  • TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR
  • H2N-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-OH
  • H-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-OH
  • H-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-
  • IGF-I (24-41)
  • IGF-I FRAG 24-41 HUMAN
  • INSULIN-LIKE GROWTH FACTOR I (24-41)
  • INSULIN-LIKE GROWTH FACTOR I FRAGMENT 24-41, HUMAN

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