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LUPEOL ACETATE

LUPEOL ACETATE Structure
LUPEOL ACETATE
  • CAS No.1617-68-1
  • Chemical Name:LUPEOL ACETATE
  • CBNumber:CB4478809
  • Molecular Formula:C32H52O2
  • Formula Weight:468.75
  • MOL File:1617-68-1.mol
LUPEOL ACETATE Property
  • Melting point 218°C
  • Boiling point 502.7±19.0 °C(Predicted)
  • Density 1.01±0.1 g/cm3(Predicted)
  • form Solid
  • color White to off-white
  • LogP 11.870 (est)
  • FDA UNII WJ3A89G0H6
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

LUPEOL ACETATE Chemical Properties,Usage,Production

  • Uses antiulcer
  • Definition ChEBI: Lupeol acetate is an organic molecular entity. It has a role as a metabolite.
  • in vivo

    Lupeol acetate (50 mg/kg; Intraperitoneal injection; 21 days) shows improvement in the mouse model of rheumatoid arthritis[3].
    Lupeol acetate (10 mg/day; Oral administration; 60 days) plays an anti-fertility role in male rats[4].

    Animal Model:DBA/1J mouse aged 8 weeks old with collagen-induced arthritis[3]
    Dosage:50 mg/kg
    Administration:Intraperitoneal injection (i.p.); 21 days
    Result:Reduced the incidence of arthritis and relieved symptoms of rheumatoid arthritis.
    Significantly decreased clinical score and paw thickness.
    Significantly lowered TNF-α and IL-1β levels in serum.
    Inhibited inflammatory activity, significantly decreased the accumulation of 18F-FDG in the joints.
    Reduced the infiltration of macrophages and bone erosion.
    Animal Model:Male albino rats of the Wistar strain aged 3.5-4 months old (170 and 200 g)[4]
    Dosage:10 mg/day
    Administration:Oral administration (p.o.); 60 days
    Result:Did not cause any significant change in the body weights, but significantly reduced in the weight of reproductive organs, i.e. testes, epididymides, seminal vesicle and ventral prostate.
    Significantly declined testicular sperm count, epididymal sperm count and motility, which resulted in reduction of male fertility by 100%.
    Interfered with spermatogenesis and significantly reduced most tubule cell types.
    Significantly reduced biochemical parameters of tissues i.e. protein, sialic acid, glycogen and cholesterol content of testes and seminal vesicular fructose.
  • IC 50 COX-2
LUPEOL ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
LUPEOL ACETATE Suppliers
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LUPEOL ACETATE Spectrum
1617-68-1, LUPEOL ACETATERelated Search:
  • Tri-Terpenoids
  • 萜类
  • 抑制剂
  • 三萜
  • 对照品
  • 植物提取物
  • C32H52O2
  • 羽扇豆醇乙酸酯/HPLC
  • 化合物LUP-20(29)-EN-3-YL ACETATE
  • 乙酸羽扇豆醇酯
  • 羽扇豆醇乙酸酯
  • 羽扇豆醇 3-乙酸酯
  • 乙酸羽扇醇酯
  • 乙酰羽扇豆醇酯
  • 1617-68-1
  • Lup-20(29)-en-3-ol, acetate, (3β)-
  • (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-Hexamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl acetate
  • Aids-076591
  • Aids076591
  • Acetic acid (1R,3ar,4S,5ar,5br,7ar,9S,11ar,11br,13ar,13br)-1-isopropenyl-3A,5A,5B,8,8,11A-hexamethyl-eicosahydro-cyclopenta[A]chrysen-9-yl ester
  • Lupa-20(29)-ene-3β-ol 3-acetate
  • Lup-20(29)-en-3β-ol acetate
  • 5α-Lupa-20(29)-ene-3β-ol acetate
  • 3β-Acetoxylupa-20(29)-ene
  • NSC 281806
  • Lupeol 3-acetate
  • LUPEOL ACETATE (REAGENT / STANDARD GRADE)
  • Lupeyl acetate
  • Lupenyl acetate
  • Lup-20(29)-en-3-yl acetate
  • Lup-20(29)-en-3-ol, acetate, (3beta)-
  • Lup-20(29)-en-3beta-ol, acetate
  • 3-O-Acetyllupeol
  • LUPEOL ACETATE(RG)
  • 3-Acetyllupeol
  • LUPEOL ACETATE

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